HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang +9 more
wiley +1 more source
Origin of subgenomes in the circumboreal, allopolyploid, carnivorous plant Drosera anglica
Abstract Premise The parentage of the widespread allopolyploid Drosera anglica, a member of the carnivorous sundew genus, remains uncertain despite over 100 years of morphological, cytological, and, more recently, molecular study. Methods Using transcriptomic and genomic data from 12 species of Drosera sect. Drosera, including four D.
Rebekah A. Mohn, Ya Yang
wiley +1 more source
Novel therapeutic strategies targeting resistance mechanisms in hematologic malignancies: from BCL2 inhibition to immunomodulatory approaches. [PDF]
Han Q, Jiang S, Chen J, Xue L.
europepmc +1 more source
Prevalence and risk factors of neglected zoonoses in Ethiopian small ruminants: a focus on Q fever, brucellosis, chlamydiosis, and toxoplasmosis. [PDF]
Alemayehu G +8 more
europepmc +1 more source
Establishment and characterization of a CCND1-rearranged non-mantle cell lymphoma cell line and patient-derived xenograft model. [PDF]
Gräf CM +15 more
europepmc +1 more source
N‐of‐1 trials offer a unique and rigorous methodology for evaluating individualized treatment responses, particularly within the context of personalized medicine. This article provides a comprehensive explanation of the conceptual and methodological underpinnings of N‐of‐1 trials, with particular emphasis on statistical techniques and considerations ...
Marcos Clint Leal De Carvalho +5 more
wiley +1 more source
Targeting Autophagy in Ovarian Cancer: The Emerging Role of Ginsenosides
ABSTRACT Background Ovarian cancer, the third most prevalent gynecological malignancy, is frequently diagnosed at an advanced stage owing to its asymptomatic early progression. Despite the application of conventional therapies, clinical management remains limited by adverse effects and the development of drug resistance.
Yuxin Guo +4 more
wiley +1 more source
A Novel Technique of Rerouting Semitendinosus Graft for Medial Collateral Ligament and Medial Patellofemoral Ligament Reconstruction - In a Polytrauma Patient with Multiligament Injury: Kakran et al. Technique. [PDF]
Kakran R, Agarwal AK, Sharma V, Tyagi V.
europepmc +1 more source
Targeting MCL1 by UMI-77 to induce mitophagy alleviates renal tubular epithelial cells injury in acute kidney injury. [PDF]
Li X +10 more
europepmc +1 more source

