Results 101 to 110 of about 30,353 (249)

Transferability of the mcr-1 Colistin Resistance Gene [PDF]

Microbial Drug Resistance, 2017
Dénervaud Tendon, Valérie, Poirel, Laurent, Nordmann, Patrice   +2 more
openaire   +4 more sources

Chemical‐Biological Fixation for Enhanced Bone Augmentation in Guided Bone Regeneration

Advanced Science, EarlyView.
M2N2ACa is an innovative injectable thermoresponsive barrier membrane adhesive to achieve reliable bone graft fixation. It provides strong wet adhesion and promotes the bio‐stabilization mediated by coagulation through controlled calcium release. This dual‐fixation strategy combines external chemical fixation and internal biological fixation via clot ...
Yu‐zhu Wang, Gao‐peng Dang, Zhi‐ting Li, Zhi‐hong Feng, Que Bai, Jia‐xin Hao, Xiao‐qing Cao, Tao Ye, Jing Li, Franklin R. Tay, Malcolm Xing, Ming Fang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Lateral Flow Immunoassay and the EDTA-Colistin Broth Disk Elution for mcr-1 gene detection in colistin-resistant E. coli and K. pneumoniae

Revista Cubana de Medicina Militar
Introduction: The global emergence of colistin-resistant Enterobacterales, especially strains carrying plasmid-mediated mcr genes, poses a significant threat to public health.
Phu Truong Thien, Ngọc Bích Trần, Thao Nguyen Thi Ngoc, Van Pham Hung, Vinh Pham Thanh, Van Tran Thi Hue, Dat Ngo Quoc   +6 more
doaj  

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

Advanced Science, EarlyView.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin, Shaojie Dong, Yue Jia, Zhao Xu, Peiqi Liu, Zhaojing Ding, Yuxin Liao, Rui Zou, Jinsong Hu, Bo Cheng, Lin Niu   +10 more
wiley   +1 more source

Lanthanum Carbonate Nanosheets Based Colloidal Hydrogel for Modulating Innate & Adaptive Tumor Immunotherapy by Augmented Cellular Pyroptosis

Advanced Science, EarlyView.
The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong, Haitao Wu, Weitao Wang, Xuan Zhang, Qian Chen, Yaoyu Hu, Zhengbao Zha   +6 more
wiley   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, EarlyView.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

Advanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song, Meng Wang, Xingyu Wu, Meng Cai, Bowen Li, Qi Wang, Xiaodong Guan, Qi Ding, Ruobing Wang, Hui Wang   +9 more
wiley   +1 more source

The first report of emerging mobilized colistin-resistance (mcr) genes and ERIC-PCR typing in Escherichia coli and Klebsiella pneumoniae clinical isolates in southwest Iran

Infection and Drug Resistance, 2019
Mojtaba Moosavian,1,2 Nasrin Emam21Infectious and Tropical Diseases Research Center, Health Research Institue, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; 2Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of
Moosavian M, Emam N
doaj  

Culture-Independent Quantitative PCR Detected Mobilized Colistin Resistance Genes (mcr-1, mcr-2, mcr-3, mcr-4, and mcr-5) in Chicken Gut Contents in Bangladesh

Sci
Inappropriate antimicrobial use in food animal farming propels antimicrobial resistance (AMR) that affects all health domains. Colistin is a ‘Reserve’ antibiotic for human treatment to be conserved for multidrug-resistant pathogens; however, it is being ...
Mamun Al Asad, Md Sarower Hossen Shuvo, Shomaia Yasmin Mitu, Sumia, Md Asief Hossain Zihadi, Ayasha Siddique Shanta, Nahidul Islam, Shamsun Nahar, Brian Godman, Salequl Islam   +9 more
doaj   +1 more source

Controlling Self‐Doping in Conjugated Polyelectrolyte Copolymers to Vary the Threshold Voltage in OECTs

Advanced Electronic Materials, EarlyView.
Two series of self‐doped conjugated polyelectrolytes are synthesized from a non‐self‐dopable building block 3MEEET and a self‐dopable building‐block 3HOT−[TMA+] or 3HOT−[SO3H] enabling precise control over the degree of self‐doping, which in turn directly governs the threshold voltage (VT) in OECTs over a wide range of 700 mV.
Julian Hungenberg, Andreas W. Erhardt, Adrian Hochgesang, John Mohanraj, Lys Sprenger, Sahar Salehi, Christopher R. McNeill, Mukundan Thelakkat   +7 more
wiley   +1 more source