Results 1 to 10 of about 973 (67)
MCR Expression Conferring Varied Fitness Costs on Host Bacteria and Affecting Bacteria Virulence
Antibiotics, 2021 Since the first report of the plasmid-mediated, colistin-resistant gene, mcr-1, nine mcr genes and their subvariants have been identified. The spreading scope of mcr-1~10 varies greatly, suggesting that mcr-1~10 may have different evolutionary advantages.
Zhihai Liu, Lu Qiao, Yang Wang
exaly +3 more sources
Frontiers in Microbiology, 2021 Mobile colistin-resistant genes (mcr) have become an increasing public health concern. Since the first report of mcr-1 in Thailand in 2016, perspective surveillance was conducted to explore the genomic characteristics of clinical carbapenem-resistant ...
Anusak Kerdsin, Watcharaporn Kamjumphol
exaly +3 more sources
Advanced Science, 2019 A growing number of mobile colistin resistance (MCR) proteins is threatening the renewed interest of colistin as a “last‐resort” defense against carbapenem‐resistant pathogens.
Yu Feng, Youjun Feng, Man Huang
exaly +2 more sources
Oral colonization of Acinetobacter baumannii in intensive care units: Risk factors, incidence, molecular epidemiology, association with the occur of pneumonia and sepsis, and infection control measures [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Oral colonization of Acinetobacter baumannii can lead to infections such as pneumonia and sepsis. We aimed to evaluate oral colonization of hospitalized patients in ICUs and to examine risk factors for oral colonization, molecular ...
Yucel Duman +9 more
doaj +1 more source
Frontiers in Microbiology, 2022 IntroductionThe global emergence of plasmid-mediated colistin resistance is threatening the efficacy of colistin as one of the last treatment options against multi-drug resistant Gram-negative bacteria.
Christa Ewers +5 more
doaj +1 more source
BMC Research Notes, 2021 Objectives The emergence of colistin-resistant Enterobacteriaceae from human and animal sources is one of the major public health concerns as colistin is the last-resort antibiotic for treating infections caused by multidrug-resistant Gram-negative ...
Kayhan Ilbeigi +5 more
doaj +1 more source
ISEc69-Mediated Mobilization of the Colistin Resistance Gene mcr-2 in Escherichia coli
Frontiers in Microbiology, 2021 ObjectivesThe emergence of mobile colistin resistance genes has compromised the efficacy of the last resort antibiotic, colistin, in clinical treatment.
Yu-Zhang He +16 more
doaj +1 more source
Frontiers in Microbiology, 2020 Retrospective studies involving the screening of frozen stored collections of samples are commonplace when a new threat emerges, but it has been demonstrated that the freeze-thaw process can affect bacterial viability.
Pedro Miguela-Villoldo +12 more
doaj +1 more source
Molecular detection of colistin resistance genes (mcr-1 to mcr-5) in human vaginal swabs
BMC Research Notes, 2018 Objective Colistin resistance has emerged worldwide and has been threatening the efficacy of one of the last-resort antimicrobials used for treatment of multidrug resistant Gram-negative bacteria. While five colistin resistance genes (mcr-1, mcr-2, mcr-3,
Jilei Zhang +8 more
doaj +1 more source
Deciphering MCR-2 Colistin Resistance
mBio, 2017 Antibiotic resistance is a prevalent problem in public health worldwide. In general, the carbapenem β-lactam antibiotics are considered a final resort against lethal infections by multidrug-resistant bacteria.
Jian Sun +11 more
doaj +1 more source