Results 31 to 40 of about 29,557 (243)

Emergence of colistin resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli strains isolated from cancer patients

Annals of Clinical Microbiology and Antimicrobials, 2019
Background Colistin resistance is mainly driven by alterations in the Gram-negative outer membrane lipopolysaccharides and is caused, in most cases, by mutations in mgrB gene.
Mai M. Zafer, Hadir A. El-Mahallawy, Asmaa Abdulhak, Magdy A. Amin, Mohamed H. Al-Agamy, Hesham H. Radwan   +5 more
doaj   +1 more source

A Multiplex SYBR Green Real-Time PCR Assay for the Detection of Three Colistin Resistance Genes from Cultured Bacteria, Feces, and Environment Samples

Frontiers in Microbiology, 2017
The aim of the study was to develop a multiplex assay for rapid detection of mcr-1, mcr-2, and mcr-3, a group of genes of conferring resistance to colistin mediated by plasmid in Enterobacteriaceae.
Jiyun Li, Jiyun Li, Xiaomin Shi, Wenjuan Yin, Yang Wang, Yang Wang, Zhangqi Shen, Shuangyang Ding, Shuangyang Ding, Shaolin Wang, Shaolin Wang   +10 more
doaj   +1 more source

High prevalence of the mcr-1 gene in retail chicken meat in the Netherlands in 2015

Antimicrobial Resistance and Infection Control, 2017
Recently, plasmid-mediated colistin resistance was reported in humans, animals and food. We studied the presence of mcr-1 and mcr-2 in Dutch retail chicken meat. The prevalence of mcr-1 was 24,8% (53/214), whereas mcr-2 was not found. The presence of mcr-
Eefje J. A. Schrauwen, Pepijn Huizinga, Nick van Spreuwel, Carlo Verhulst, Marjolein F. Q. Kluytmans-van den Bergh, Jan A. J. W. Kluytmans   +5 more
doaj   +1 more source

Virulence and antimicrobial resistance profiles of Escherichia coli encoding mcr gene from diarrhoeic weaned piglets in Korea during 2007–2016

Journal of Global Antimicrobial Resistance, 2020
Objective: This study aimed to analyse the presence of mcr genes and virulence genes in Escherichia coli (E. coli) isolates from diarrhoeic piglets between 2007–2016 in Korea. Methods: A total of 364 E.
Kyung-Hyo Do, Ho-Eun Park, Jae-Won Byun, Wan-Kyu Lee   +3 more
doaj   +1 more source

Prevalence and Some Possible Mechanisms of Colistin Resistance Among Multidrug-Resistant and Extensively Drug-Resistant Pseudomonas aeruginosa

Infection and Drug Resistance, 2020
Rehab M Abd El-Baky, 1, 2 Salwa M Masoud, 1 Doaa S Mohamed, 2 Nancy GFM Waly, 1 Engy A Shafik, 3 Dina A Mohareb, 4 Azza Elkady, 5 Mohamed M Elbadr, 6 Helal F Hetta 7, 8 1Department of Microbiology and Immunology, Faculty of Pharmacy, Minia University ...
Abd El-Baky RM, Masoud SM, Mohamed DS, Waly NGFM, Shafik EA, Mohareb DA, Elkady A, Elbadr MM, Hetta HF   +8 more
doaj  

HPLC-PDA Analysis and Anti-inflammatory Effects of Mori Cortex Radicis

Natural Product Communications, 2013
Mori Cortex Radicis (MCR, Moraceae) is used traditionally in the treatment of jaundice, hematemesis, edema, and pollakisuria in Korea. In this study, the anti-inflammatory effects of MCR extract were investigated using RAW 264.7 cells.
Chang-Seob Seo, Hye-Sun Lim, Soo-Jin Jeong, Hyekyung Ha, Hyeun-Kyoo Shin   +4 more
doaj   +1 more source

Microbiological surveillance of plasmid mediated colistin resistance in human Enterobacteriaceae isolates in Romagna (Northern Italy): August 2016–July 2017

International Journal of Infectious Diseases, 2018
Objectives: To start a surveillance program to investigate the possible diffusion of mobilized colistin resistance genes in Enterobacteriaceae strains isolated in the Unit of Microbiology of the Great Romagna Hub Laboratory.
F. Del Bianco, M. Morotti, M.F. Pedna, P. Farabegoli, V. Sambri   +4 more
doaj   +1 more source

Molecular Epidemiology of Extensively Drug-Resistant mcr Encoded Colistin-Resistant Bacterial Strains Co-Expressing Multifarious β-Lactamases

Antibiotics, 2021
Plasmid-mediated colistin resistance (Col-R) conferred by mcr genes endangers the last therapeutic option for multifarious β-lactamase-producing bacteria.
Hasan Ejaz, Sonia Younas, Muhammad Usman Qamar, Kashaf Junaid, Abualgasim Elgaili Abdalla, Khalid Omer Abdalla Abosalif, Ayman Ali Mohammed Alameen, Mohammed Yagoub Mohammed Elamir, Naveed Ahmad, Sanaa Samir Mohamed Hamam, Eman Hosney Mohammed Salem, Syed Nasir Abbas Bukhari   +11 more
doaj   +1 more source

Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli

mBio, 2017
The mobile colistin resistance gene mcr-1 has attracted global attention, as it heralds the breach of polymyxins, one of the last-resort antibiotics for the treatment of severe clinical infections caused by multidrug-resistant Gram-negative bacteria.
Wenjuan Yin, Hui Li, Yingbo Shen, Zhihai Liu, Shaolin Wang, Zhangqi Shen, Rong Zhang, Timothy R. Walsh, Jianzhong Shen, Yang Wang   +9 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source