Results 221 to 230 of about 30,237 (249)
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Colistin resistance gene mcr-1 in gut flora of children
International Journal of Antimicrobial Agents, 2017The aim of this study was to determine the prevalence and transmission mechanism(s) of mcr-1 in the gut flora of children. Faecal samples (n = 173) were obtained from non-diarrhoea patients at the Children's Hospital of Zhejiang University (Hangzhou, China). PCR-based analysis indicated that 17 isolates from 9.8% of the samples were positive for mcr-1,
Yan-Yan, Hu +6 more
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Impact of the colistin resistance gene mcr-1 on bacterial fitness
International Journal of Antimicrobial Agents, 2018A Klebsiella pneumoniae isolate harbouring a 217 kb IncHI2-type plasmid (pKP2442) encoding the colistin resistance gene mcr-1 was isolated from a leukaemia patient. pKP2442 was mobilised by intragenus and intergenus transconjugation from the clinical isolate to Escherichia coli J53 (transconjugation frequency 6.86 × 10-8 ± 5.57 × 10-8) and K ...
Tietgen, Manuela +6 more
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Population dynamics models based on the transmission mechanism of MCR-1
Physica A: Statistical Mechanics and its Applications, 2019zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Qu, Leilei +4 more
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Swine waste: A reservoir of high-risk blaNDM and mcr-1
Science of The Total Environment, 2019Multidrug resistance associated with pigs not only affects pig production but also threatens human health by influencing the farm surrounding and contaminating the food chain. This paper focused on the occurrence and prevalence of high-risk resistance genes (using blaNDM and mcr-1 as marker genes) in two Chinese swine farms, and investigated their fate
Fengxia, Yang +3 more
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Microbial drug resistance (Larchmont, N.Y.), 2021
Aims: mcr-1 and blaNDM-1 co-harboring isolates have been reported, usually reside on different plasmids, suggesting co-transfer possibility of the two genes from separate donors to the same recipient strain. This study aims at screening and characterization of mcr-1 carrying Enterobacteriaceae in Northern China, and studying the transfer ability of mcr-
Zhenwei, Liang +9 more
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Aims: mcr-1 and blaNDM-1 co-harboring isolates have been reported, usually reside on different plasmids, suggesting co-transfer possibility of the two genes from separate donors to the same recipient strain. This study aims at screening and characterization of mcr-1 carrying Enterobacteriaceae in Northern China, and studying the transfer ability of mcr-
Zhenwei, Liang +9 more
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American Journal of Infection Control, 2018
Tijera Bell, Thi Dang, Whitney Thorpe
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Tijera Bell, Thi Dang, Whitney Thorpe
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Understanding mcr-1 mediated polymyxin resistance in Enterobacteriaceae
2020Antibiotic resistance is a major threat to humanity. Many of us have been taking antibiotics for granted. The emergence of drug-resistant ‘superbugs’ has brought back an ‘old’ class of antibiotic, the polymyxins. Unfortunately, this last-line of defence is breached.
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Identification of novel mobile colistin resistance gene mcr-10
Emerging Microbes and Infections, 2020Yu Feng, Li Wei, Mei Kang
exaly
MCR-1-producing Klebsiella pneumoniae outbreak in China
The Lancet Infectious Diseases, 2017Guo-Bao, Tian +6 more
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