Results 141 to 150 of about 124,585 (291)

Combination of aza-Friedel Crafts MCR with Other MCRs Under Heterogeneous Conditions

open access: yesCatalysts
Multicomponent reactions (MCRs) enable the efficient assembly of complex small molecules via multiple bond-forming events in a single step. However, individual MCRs typically yield products with similar core structures, limiting access to larger, more intricate scaffolds.
Giovanna Bosica, Roderick Abdilla
openaire   +1 more source

The International Classification of Cognitive Disorders in Epilepsy (IC‐CoDE) Portal: An open source resource for neuropsychological research in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective The International Classification of Cognitive Disorders in Epilepsy (IC‐CoDE) is a consensus‐based, empirically‐driven approach to standardize cognitive phenotyping in epilepsy research that has quickly garnered interest within the epilepsy community. However, manually generating IC‐CoDE phenotypes in group data is laborious and time‐
Robyn M. Busch   +11 more
wiley   +1 more source

Abnormal functional connectivity patterns in temporal lobe epilepsy—An international ENIGMA‐epilepsy study

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives Temporal lobe epilepsy (TLE) impacts multiple brain networks. Aberrant functional connectivity has been demonstrated in resting‐state networks (RSNs) that mediate higher brain functions in TLE. This study aimed to identify the reproducible patterns of altered functional connectivity in TLE in a large, international cohort through ...
Victoria Ives‐Deliperi   +28 more
wiley   +1 more source

Comparison of physicochemical, rheological, and digestibility properties of starch isolated from plantain (Musa paradisiaca) using different methods

open access: yesFood Biomacromolecules, EarlyView.
Abstract The present work aimed to evaluate the effect of different isolation methods (distilled water, sodium hydroxide, and potassium metabisulfite) on the properties of plantain starch and compared with flour. It was hypothesized that chemical steeping enhanced yield, techno‐functional properties, and resistant starch without disrupting native ...
Tanvir Ahmed Laskar   +3 more
wiley   +1 more source

General Introduction to MCRs

open access: yes, 2015
Multicomponent reactions (MCRs) are mostly experimentally simple to perform, often without the need of dry conditions and inert atmosphere. MCRs provide a huge chemical diversity and currently more than 300 different scaffolds have been described in the chemical literature.
Dömling, Alexander   +1 more
openaire   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

open access: yesFood Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei   +4 more
wiley   +1 more source

Freeze‐resistant, conductive semi‐interpenetrating network hydrogels enable oxidative stress regulation and enhanced wound healing

open access: yesInterdisciplinary Medicine, EarlyView.
A multifunctional SFMA9/PF1 semi‐interpenetrating hydrogel with excellent conductivity, antioxidant activity, and freeze resistance effectively regulates the wound microenvironment, reduces oxidative stress and inflammation, promotes angiogenesis, and accelerates full‐thickness skin regeneration.
Xiaomin Sun   +7 more
wiley   +1 more source

Evaluation of FilmArray Multiplex PCR Test Results in Bloodstream Infections in Oncological Patients

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
In this study conducted at an oncology hospital, BCID2 panel results for the rapid identification of microorganisms and resistance genes in positive blood culture samples were compared with conventional culture methods. The BCID2 panel provided faster results and showed a high correlation with traditional methods.
İpek Mumcuoğlu   +6 more
wiley   +1 more source

Evaluation of Soluble Triggering Receptor Expressed on Myeloid Cells 2 (sTREM2) in Cerebrospinal Fluid, Serum, and Plasma Using the Fully Automated Lumipulse Platform

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Relationship between serum and CSF sTREM2 concentration. ABSTRACT Background In this study, we first evaluated the relationship between sTREM2 concentrations in CSF, serum, and plasma of Alzheimer's disease (AD) patients using the newly developed Lumipulse G sTREM2 assay.
Luisa Agnello   +9 more
wiley   +1 more source

Bioanalytical TERS and Advanced Data Processing Methods

open access: yesJournal of Raman Spectroscopy, EarlyView.
Tip‐enhanced Raman spectroscopy delivers label‐free, subnanometer vibrational imaging of biological systems. Recent advances in instrumentation, data analysis, and ambient/liquid operation enable surface‐selective mapping of molecular heterogeneity in proteins, nucleic acids, membranes, and viruses, positioning TERS as a powerful platform for nanoscale
Sarika Joshi   +6 more
wiley   +1 more source

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