Results 91 to 100 of about 62,976 (303)

Hematological Profiles and Serum Cytokine Levels in Patients With Breast Cancer in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis of Current Evidence. [PDF]

Health Sci Rep
ABSTRACT Background and Aim Breast cancer is a leading cause of morbidity and mortality in Low‐ and Middle‐Income Countries (LMICs). Hematological and inflammatory markers offer accessible, low‐cost tools for patient assessment; hence, this study synthesized evidence on hematological parameters and serum cytokine levels in breast cancer patients from ...
Duneeh RV, Addai-Mensah O, Sackey B, Adankwah E, Afriyie EY, Agyemang V, Kwadzokpui PK, Ativi E, Klugah MA, Amponsah FA, Ablordey K.   +10 more
europepmc   +2 more sources

Calculation of Critical Values for Somerville's FDR Procedures [PDF]

A Fortran 95 program has been written to calculate critical values for the step-up and step-down FDR procedures developed by Somerville (2004). The program allows for arbitrary selection of number of hypotheses, FDR rate, one- or two-sided hypotheses ...
Paul N. Somerville
core  

NILAI MEAN CORPUSCULAR VOLUME (MCV) PADA DOMBA EKOR GEMUK, DOMBA LOKAL DAN PERSILANGANNYA (MEAN CORPUSCULAR VOLUME (MCV) VALUE IN FAT TAILED SHEEP, LOCAL SHEEP AND THE CROSSBRED SHEEP)

, 2022
ABSTRAKDomba ekor gemuk, domba lokal, dan persilangannya merupakan domba yang memiliki karakterisitik yang berbeda satu dengan lainnya. Mean corpuscular volume (MCV) atau volume rata-rata dari masing-masing red blood cell (RBC) adalah sebuah indeks yang ...
APRILIA RAHMAYANI
core  

HUBUNGAN RET-HE TERHADAP INDEKS ERITROSIT (MCV, MCH, MCHC) PADA IBU HAMIL DI PUSKESMAS JAGIR SURABAYA [PDF]

, 2020
Ret-He merupakan suatu parameter pengembangan alat hematologi otomatis terbaru yangmengukur kadar hemoglobin dalam retikulosit yang berfungsi menilai zat besi dalam tubuh.
HIMAWAN, SULLI DWI
core  

Direct SMBH Formation Driven by Runaway Stellar Collisions in Globally Unstable Stellar Systems

Astronomische Nachrichten, EarlyView.
ABSTRACT The fueling problem addresses the ultimate fate of the reservoirs of gas and stars driven into the deepest gravitational potential wells of galaxies, thus it may contain the Universe's densest concentrations of gas and stars. This raises a key question: does the infalling material collapse directly into a supermassive black hole, or can it ...
Marcelo C. Vergara, Andrés Escala
wiley   +1 more source

Mapping of the MCV LT and Brd4 interaction sites.

, 2012
A. Schematic diagrams of full-length MCV LT protein and truncation mutants used for mapping. All MCV LT fragments were expressed from a pcDNA4C plasmid encoding an Xpress epitope tag. B. Mapping the Brd4 binding site on MCV LT.
Jianxin You (121729), Christopher B. Buck (121726), Jing Li (10611), Rachel M. Schowalter (121719), Xin Wang (91924), Jing Jiao (121723)   +5 more
core   +1 more source

Engineered immunostimulatory H2O2‐producing microreactors driven by yeast as localized living cancer therapeutics

BMEMat, EarlyView.
Engineered yeast microreactors that produce H2O2 within tumors enable selective cancer cell killing while releasing immunostimulatory components, effectively suppressing local tumor growth and activating systemic antitumor immunity, with further efficacy enhanced by anti‐PD‐1 therapy and transarterial embolization.
Wenqian He, Chunjie Wang, Minming Chen, Weihao Yang, Bin Yu, Yuhang Hu, Hengze Ding, Yifan Yan, Zhijuan Yang, Liangzhu Feng   +9 more
wiley   +1 more source

Disease-driven loss of inactive HSD17B13 isoforms enhances enzymatic output in MASH and counters protective rs72613567:TA variant

JHEP Reports
Background & Aims: We investigated whether liver disease alters HSD17B13 isoform expression, identifying selective loss of exon 2-skipped variants and uncovering variant B as a structured, noncoding RNA with silencing potential.
John Min, Mulugeta Seneshaw, Faridoddin Mirshahi, Hae-Ki Min, Arun J. Sanyal   +4 more
doaj   +1 more source

How to Optimize Healthy Volunteer Screening and Enrolment in Clinical Trials: A Qualitative and Quantitative Approach to Evaluate Processes and Healthy Volunteers' Perceptions

Clinical Pharmacology &Therapeutics, EarlyView.
Healthy volunteers (HVs) are essential for phase I trials, yet their recruitment and screening remain resource‐intensive and ethically complex. High screening failure (SF) rates highlight the need to evaluate and understand all aspects of the enrolment processes. We analyzed SF patterns in a large German HV cohort and explored participants' motivations,
Evelyn Krohmer, Manuela König, Cathrin J. Vogt, Marina Streckebein, Sybille Baumann, Max Blumenstock, Ruwen Böhm, Fabian Müller, Nadja Struß, Viktoria S. Wurmbach, Antje Blank   +10 more
wiley   +1 more source

Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1

Frontiers in Microbiology, 2018
Merkel cell polyomavirus (MCV) plays a causal role in ∼80% of Merkel cell carcinomas (MCC). MCV is clonally integrated into the MCC tumor genome, which results in persistent expression of large T (LT) and small T (sT) antigen oncoproteins encoded by the ...
Celestino Velásquez, Yutaka Amako, Yutaka Amako, Alexis Harold, Tuna Toptan, Tuna Toptan, Yuan Chang, Yuan Chang, Masahiro Shuda, Masahiro Shuda   +9 more
doaj   +1 more source