Results 101 to 110 of about 62,976 (303)

Coexistence of immunophenotypically normal and aberrant mast cells in patients with clonal mast cell diseases associates with more indolent subtypes and less severe disease characteristics

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Aberrant antigen expression on mast cells (MCs) is one of the most accurate diagnostic markers for clonal MC diseases (CMCD). Although the coexistence of normal and pathologic MCs is frequently seen, the disease characteristics associated with it have been minimally investigated.
Abdulrazzaq Alheraky, Kees Meijer, Marije Nijk, Saskia K. Klein, Hanneke N. G. Oude Elberink, Ido P. Kema, André B. Mulder   +6 more
wiley   +1 more source

The Changes of Erythrocyte Indices in Pesticide Factory Workers

Medical Laboratory Journal, 2008
Background and Objectives: Erythrocyte indices are helpful for monitoring the erythrocyte synthesis and liver condition. The pesticide factories’ staff are being exposed to poisoning.
HR Joshaghani, KH Kalavi, N Namjoo
doaj  

Red Blood Cell Surface Proteins and Cryopreservation for Tracking Altered Erythropoiesis

Drug Testing and Analysis, EarlyView.
Recombinant human erythropoietin altered red blood cell surface protein expression, but responses were inconsistent and accompanied by substantial baseline variability. Although cryopreservation reduced analytical variability, it did not improve biomarker performance, indicating limited utility for detecting altered erythropoiesis. ABSTRACT The present
Martin Thomassen, Thomas Bonne, Jonathan Graae, Sophie Møller, Ylva Hellsten, Henrik Sørensen, Nikolai B. Nordsborg, Jacob Bejder   +7 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

From bodyweight to biomarkers: Season‐associated metabolic, endocrine and haematological shifts in breeding stallions

Equine Veterinary Journal, EarlyView.
Abstract Background Breeding stallions are subjected to sustained seasonal metabolic, endocrine, and immune demands requiring systemic energy engagement. Prospective longitudinal data in the same individuals are limited. Objectives To screen adaptive responses of breeding stallions of clinical relevance through longitudinal characterisation of temporal
Maria Grazia Cappai, Morrone Sarah, Senes Alice, Taras Andrea, Biggio Giampaolo, Cherchi Raffaele   +5 more
wiley   +1 more source

Glycosaminoglycans and sialylated glycans sequentially facilitate Merkel cell polyomavirus infectious entry.

PLoS Pathogens, 2011
Merkel cell polyomavirus (MCV or MCPyV) appears to be a causal factor in the development of Merkel cell carcinoma, a rare but highly lethal form of skin cancer.
Rachel M Schowalter, Diana V Pastrana, Christopher B Buck   +2 more
doaj   +1 more source

Research progress on flexible MXene‐based materials in advanced energy storage devices: From preparation strategies to device applications

FlexMat, EarlyView.
This review summarizes MXene synthesis and flexible electrode fabrication for FESDs, highlighting their potential owing to high conductivity and flexibility, and outlines future research directions. Abstract The rapid development of wearable and portable electronics has created demand for flexible energy storage systems (FESDs) that not only exhibit ...
Nanxi Miao, Ying Lu, Xing Gao, Lingzi Pan, Meng Gao, Chenxi Zhang, Ming Liu, Shizhong Wang, Zhongyu Weng, Huan Pang, Huijie Zhou   +10 more
wiley   +1 more source

Safety and Metabolic Effects of Withania somnifera Seed Extract and Powder in Rats: Insights From DPP‐4 Molecular Docking

Food Safety and Health, EarlyView.
Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid, Muhammad Waqar, Muhammad Tauseef Sultan, Muhammad Maaz, Ahmad Mujtaba Noman, Hassan Raza, Muhammad Israr, Djilali Benabdelmoumene, Abdifetah Ibrahim Omar   +8 more
wiley   +1 more source

Diagnostic value of anti-MCV antibodies in differentiating early inflammatory arthritis

, 2009
Objectives To evaluates the diagnostic performance of the anti-CCP2, anti-CCP3 and anti-mutated citrullinated vimentin (anti-MCV) tests in differentiating rheumatoid arthritis (RA) from other forms of arthritis in a clinical setting of early arthritis ...
Huizinga, T.W.J., Damjanovska, L., Thabet, M.M., Levarth, E.W.N., Voort, E.I. van der, Stoeken-Rijsbergen, G., Helm-van Mil, A.H.M. van der, Toes, R.E.M., E. I. van der Voort, M. M. Thabet, G. Stoeken-Rijsbergen, E. W. N. Levarth, T. W. J. Huizinga, L. Damjanovska, R. E. M. Toes, A. H. M. van der Helm-van Mil   +15 more
core   +1 more source

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source