Results 41 to 50 of about 47,080 (263)

Anemia in Newly Diagnosed Cases with Liver Cirrhosis

Acta Medica Bulgarica
Between 50% and 87% of cases with liver cirrhosis have a concomitant anemic syndrome, which is the most common hematological abnormality on routine examination.
Mihaylova M., Strashilov S., Tonchev P.
doaj   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Dual‐Responsive Hydrogels Integrate Bioelectrical Stimulation and Piezo‐Photocatalysis for Regenerative Treatment of Infected Wounds

Advanced Science, EarlyView.
A wireless, dual‐responsive hydrogel (PVA/(PVDF‐TrFE)/BiOClBr@PDA) is developed to promote efficient regeneration of infected wounds by integrating piezoelectric stimulation with piezo‐photocatalytic pathways. Under simultaneous light and ultrasonic stimulation, the hydrogel generates therapeutic electrical cues and reactive oxygen species, disrupting ...
Baoying Dai, Wenxuan Qie, Xiaoye Li, Jingben Zheng, Ao He, Heng Dong, Jiangjiang Yan, Hao Zhang, Ziheng Pan, Hang Yin, Chuyi Zhou, Rui Kong, Hao Wang, Binghan Dai, Yannan Xie, Zhiqun Lin   +15 more
wiley   +1 more source

Hematological indices and undiagnosed anemia among adult male patients in Makkah, Saudi Arabia

Romanian Journal of Laboratory Medicine
Background: Hematological indices are essential tools for evaluating physiological and pathological conditions, particularly anemia, which may remain undiagnosed in adult males due to the absence of specific clinical symptoms.
Zaini Rana Ghazi
doaj   +1 more source

An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer

Advanced Science, EarlyView.
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li, Anguo Zhao, Qi Zhuang, Lei Peng, Rui Liang, Jiadong Zhao, Yang Liu, Dashi Deng, Peng Yu, Xiqi Peng, Shaohua Zhang, Song Wu   +11 more
wiley   +1 more source

Etiological Profile of Macrocytic Anemia in Patients Presenting to a Tertiary Care Hospital

Assam Journal of Internal Medicine
Background: Macrocytic anemia is a common hematological finding with a wide range of causes, from nutritional deficiencies to systemic illnesses and bone marrow disorders.
Akhila Nampally, Deme Swaroopa, Adiraju Krishna Prasad   +2 more
doaj   +1 more source

A clinicopathological investigation on morphological alterations of red blood cells among treated and untreated type II diabetes mellitus patients

Indian Journal of Pathology and Microbiology
Introduction: The cross-sectional study was designed to analyze the morphological changes occurring in red blood cells (RBCs) among patients with type II diabetes mellitus (type II DM) and to investigate the association of these changes with various ...
Madhurima Basak, Surya Kanta Dey, Sourav Ghosh, Dipanjan Bhattacharjee, Arun Nayek, Abhishek Janaa   +5 more
doaj   +1 more source

Bromodomain protein Brd4 plays a key role in Merkel cell polyomavirus DNA replication.

PLoS Pathogens, 2012
Merkel cell polyomavirus (MCV or MCPyV) is the first human polyomavirus to be definitively linked to cancer. The mechanisms of MCV-induced oncogenesis and much of MCV biology are largely unexplored.
Xin Wang, Jing Li, Rachel M Schowalter, Jing Jiao, Christopher B Buck, Jianxin You   +5 more
doaj   +1 more source

Detection of Molluscum Contagiosum Virus (MCV) DNA in the Plasma of an Immunocompromised Patient and Possible Reduction of MCV DNA With CMX-001 [PDF]

The Journal of Infectious Diseases, 2012
Molluscum contagiosum virus (MCV) is a poxvirus that causes localized papules in healthy persons. We evaluated a woman with severe immunodeficiency and disseminated MCV. During treatment with CMX-001, an antiviral with activity against other poxviruses, MCV DNA was detected in 20% of plasma samples.
Jeffrey I, Cohen, Wilmer, Davila, Mir A, Ali, Siu-Ping, Turk, Edward W, Cowen, Alexandra F, Freeman, Kening, Wang   +6 more
openaire   +2 more sources