Results 41 to 50 of about 62,976 (303)

Coordinated viral gene expression during MCV replication in 293 cells.

open access: yes, 2013
One microgram of recircularized MCV genomes (wild-type MCV-HF or replication-defective MCV-Rep−) was transfected into 293 cells. Immunoblotting was performed to examine T antigen expression over 5 days (indicated by hollow arrows) and VP1 protein ...
Hyun Jin Kwun (347603)   +6 more
core   +1 more source

Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns

open access: yesArthritis Care &Research, Accepted Article.
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen   +24 more
wiley   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar   +11 more
wiley   +1 more source

Patra index and Mentzer index – A retrospective comparative study to differentiate Beta-Thalassemia Trait from iron deficiency anemia

open access: yesJournal of Family Medicine and Primary Care
Introduction: Beta-thalassemia trait (BTT) and iron deficiency anemia (IDA) are the two most common causes of microcytic hypochromic anemia. Differentiating these conditions is crucial, particularly in school-aged children, to reduce the societal burden ...
Satyabrata Patra   +3 more
doaj   +1 more source

Obliquity of the Stapes in Otosclerosis: A New Radiological Sign

open access: yesInternational Archives of Otorhinolaryngology, 2016
Introduction Observing the obliquity of stapes by closely scrutinizing the HRCT temporal bone in otosclerosis revealed a reliable and consistent finding. This finding can add to the existing radiological criteria in diagnosis of otosclerosis.
Veluswamy Anand   +2 more
doaj   +1 more source

Human Brd4 interacts with MCV LT.

open access: yes, 2012
A. MCV LT Co-IP with Brd4. C33A cells were transfected with pcDNA4C-MCV LT. Nuclear extracts IPed with normal rabbit IgG (IgG) or the polyclonal Brd4NA antibody (Brd4) were immunoblotted for MCV LT and Brd4.
Jianxin You (121729)   +5 more
core   +1 more source

MCV-miR-M1 targets the host-cell immune response resulting in the attenuation of neutrophil chemotaxis [PDF]

open access: yes, 2018
Virus-encoded miRNAs are emerging as key regulators of persistent infection and host-cell immune evasion. Merkel cell polyomavirus (MCPyV), the predominant aetiological agent of Merkel cell carcinoma (MCC), encodes a single miRNA, MCV-miR-M1, which ...
James R. Boyne   +14 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Arthritic disease activity: anti-MCV positive versus anti-MCV negative patients

open access: yes, 2011
Statistical comparisons were performed between anti-mutated citrullinated vimentin (anti-MCV)-positive and anti-MCV-negative patients at the indicated time points.
Jennie Ursum (91648)   +6 more
core   +1 more source

Dual‐Responsive Hydrogels Integrate Bioelectrical Stimulation and Piezo‐Photocatalysis for Regenerative Treatment of Infected Wounds

open access: yesAdvanced Science, EarlyView.
A wireless, dual‐responsive hydrogel (PVA/(PVDF‐TrFE)/BiOClBr@PDA) is developed to promote efficient regeneration of infected wounds by integrating piezoelectric stimulation with piezo‐photocatalytic pathways. Under simultaneous light and ultrasonic stimulation, the hydrogel generates therapeutic electrical cues and reactive oxygen species, disrupting ...
Baoying Dai   +15 more
wiley   +1 more source

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