Results 51 to 60 of about 3,368,671 (295)

Raymond Alexanian, MD, Oral History Interview, June 5, 2014 [PDF]

open access: yes, 2014
Major Topics Covered: Committees at MD Anderson: Research Committee, Surveillance Committee, Transfusion Task Force, Faculty Classification Committee; The research and cultural environment of MD Anderson under Dr. R.
Rosolowski, Tacey A., PhD   +1 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Thomas W. Burke, MD, Oral History Interview, April 29, 2014 [PDF]

open access: yes, 2014
Major Topics Covered: Developing networks to serve MD Anderson MD Anderson culture: changes and continuities amid growth MD Anderson’s financial challenges and strategies to navigate themhttps://openworks.mdanderson.org/mchv_interviewsessions/1220 ...
Burke, Thomas W., MD   +1 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Etude de la cellule de commutation d’une alimentation à découpage dans le cadre de la compatibilité électromagnétique

open access: yesRevue des Énergies Renouvelables, 2014
La Compatibilité Electromagnétique, CEM, apparaît aujourd’hui comme l’une des contraintes majeures de la conception des structures de l’électronique de puissance et plus précisément sur les alimentations à découpage.
A. Lakrim, D. Tahri
doaj  

Chapter 12: The Competing Priorities of Patient Care and Research in the Past and Future of MD Anderson, and the Unsung Hero Clinicians at MD Anderson

open access: yes, 2019
Dr. Byers gives his perspective on the priority of personal patient care in MD Anderson’s past, Dr. R. Lee Clark’s emphasis on it relative to research, the trend of its deemphasis under subsequent MD Anderson presidents, and the necessity for its ...
Balch, Charles M., MD, Byers, Robert, MD
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Thomas W. Burke, MD, Oral History Interview, March 18, 2014 [PDF]

open access: yes, 2014
Major Topics Covered: Gynecologic Oncology at MD Anderson and multi-disciplinary care Development of multi-disciplinary care at MD Anderson Roles as Physician-in-Chief Developing MD Anderson support serviceshttps://openworks.mdanderson.org ...
Burke, Thomas W., MD   +1 more
core  

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