Results 61 to 70 of about 3,368,671 (295)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
BMC Surgery, 2017 Background Meckel’s diverticulum is the most common congenital malformation of the gastrointestinal tract, and it represents a persistent remnant of the omphalomesenteric duct.
Georges A. Abizeid, Hager Aref
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Construction of all MDS and involutory MDS matrices
Advances in Mathematics of CommunicationsIn this paper, we propose two algorithms for a hybrid construction of all $n\times n$ MDS and involutory MDS matrices over a finite field $\mathbb{F}_{p^m}$, respectively. The proposed algorithms effectively narrow down the search space to identify $(n-1) \times (n-1)$ MDS matrices, facilitating the generation of all $n \times n$ MDS and involutory MDS
Yogesh Kumar +4 more
openaire +3 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Chapter 18: MD Anderson Presidents
, 2012 Here Dr. Goepfert gives his views of the leadership styles of MD Anderson’s first three presidents. He describes R. Lee Clark as a “unique leader” with a strong character and decisive leadership style.
Rosolowski, Tacey A., PhD +1 more
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John Mendelsohn, MD, Oral History Interview, 2005 [PDF]
, 2005 Major Topics Covered: Personal and educational background Research: evolution of research; monoclonal antibodies MD Anderson research; building the basic sciences; South Campus and the research institutes; building collaborative culture and ...
Mendelsohn, John, MD +2 more
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chapter 21: The MD Anderson Network: Origins, Mission, and Lessons of MD Anderson Orlando
, 2014 In this chapter, Dr. Burke talks about becoming Vice President of the MD Anderson Cancer Network, established early in 2014. He gives background on how the Network began. Next, he explains why he was appointed to the position and his personal reasons for
Burke, Thomas W., MD +1 more
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