Results 81 to 90 of about 3,368,671 (295)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Levetiracetam and Valproic Acid: Effects on the Liver Functions and Ammonia Level in Children

open access: yesÇukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Purpose: There is evidence that levetiracetam and valproic acid causes a changes of serum ammonia level and liver function tests. The aim of this study was to evaluate the liver function parameters and ammonia level in children with seizures on treatment
Faruk Incecik   +2 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Il design come bene culturale

open access: yesMD Journal, 2019
«Da tutte queste cose emerge una forma del tempo, si delinea un tratto visibile dell’identità collettiva, sia essa tribù, classe o nazione. Questo autoritratto riflesso nelle cose serve al gruppo come guida e punto di riferimento per il futuro e diviene ...
Emanuela Bonini Lessing   +3 more
doaj  

Chapter 07: Dr. R. Lee Clark, Surgeon & Chief, MD Anderson Cancer Hospital

open access: yes, 2019
Thoughts on the Dr. R. Lee Clark’s reputation, area of expertise, and degree of control over surgical practices at MD Anderson. Dr. Byers talks about how Dr.
Balch, Charles M., MD, Byers, Robert, MD
core  

John Stroehlein, MD, Oral History Interview, December 12, 2012 [PDF]

open access: yes, 2012
Major Topics Covered: Personal and educational background; military experience; retirement Working at Methodist Hospital; MD Anderson in comparison to other institutions Gastroenterology and oncology: history and evolution; development of team ...
Stroehlein, John, MD   +1 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Frederick F. Becker, MD, Oral History Interview, May 17, 2012 [PDF]

open access: yes, 2012
Major Topics Covered: Building MD Anderson’s Department of Pathology Building MD Anderson’s research culture: multi-disciplinary research, excellence, fundraising South Campus Working with MD Anderson presidents The institutional and financial stress ...
Becker, Frederick F., MD   +1 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Chapter 21: Expanding MD Anderson’s Reputation

open access: yes, 2012
Dr. Hill begins this chapter by explaining why so many ENT cancers were referred to MD Anderson to have the successful, less disfiguring surgeries for people “who were supposed to be dead.” (He vividly describes the process of “walking a flap [of skin]”
Hill, C. Stratton, Jr. MD   +1 more
core  

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