Results 101 to 110 of about 3,368,671 (295)
Chapter: 09 MD Anderson Presidents
, 2013 Dr. Bodey begins this chapter on the MD Anderson presidents by recalling the late Dr. R. Lee Clark was “like a general” and a very wise man. He recalls Dr. Charles LeMaistre was a “Fine Christian gentleman” who projected a good image for the institution.
Bodey, Gerald P., MD +1 more
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Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Louise Connally Strong, MD, Oral History Interview, August 8, 2012 [PDF]
, 2012 Major Topics Covered: Personal and educational background Overview and history of oncology genetics in the sixties and seventies Working with Alfred Knudson Research: longitudinal studies of inherited genetics patterns of neuroblastoma, aniridia, and ...
Strong, Louise Connally, MD +1 more
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Chapter 04: Multidisciplinary Care and the MD Anderson Algorithms
, 2017 In this chapter, Dr. Rodriguez defines the MD Anderson algorithms of care and explains how they were created and are continually evolving, based on current research.
Rodriguez, Alma, MD +1 more
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Walter Franklin Baile, MD, Oral History Interview, October 25, 2016 [PDF]
, 2016 Major Topics Covered: Psychiatry at MD Anderson Developing communications teaching at MD Anderson The iCare communications program: services, institutional support for Institutional change with shift in administration, 2011 and Ronald DePinhohttps ...
Baile, Walter F., MD +1 more
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
James D. Cox, MD, Oral History Interview, January 3, 2013 [PDF]
, 2013 Major Topics Covered: Personal and educational background MD Anderson research culture Clinical trials: controversy over, ethical issues; The Radiation Oncology Group Radiation oncology at MD Anderson; the Division of Radiation Oncologyhttps ...
Cox, James D., MD +1 more
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