Results 121 to 130 of about 3,368,671 (295)
John Stroehlein, MD, Oral History Interview, December 5, 2012 [PDF]
, 2012 Major Topics Covered: Personal and educational background; military experience; retirement Working at Methodist Hospital; MD Anderson in comparison to other institutions Gastroenterology and oncology: history and evolution; development of team ...
Stroehlein, John, MD +1 more
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Chapter 13: Cultivating Leadership at MD Anderson
, 2012 Here Dr. Bruner talks about leadership development at MD Anderson, beginning with the courses she took via the American College of Physician Executives.
Bruner, Janet M., MD +1 more
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Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Chapter 21: Views of Charles A. LeMaistre and MD and R. Lee Clark, MD
, 2001 In this chapter, Dr. Freireich talks about Dr. LeMaistre; how, in his view, Dr. LeMaistre abused his power as president; and why he thinks MD Anderson was hated by other state institutions.https://openworks.mdanderson.org/mchv_interviewchapters/1168 ...
Freireich, Emil J, MD, Brunet, Lesley W.
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Chapter 24: Transitional Moments in MD Anderson History
, 2015 Dr. Rodriguez sketches key moments of change in MD Anderson history since her arrival. She first talks about the eighties and the “growing consciousness that MD Anderson is an economic entity,” moving on to the nineties and the complexities that evolved ...
Rodriguez, Alma, MD +1 more
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FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Gabriel N. Hortobagyi, MD, Oral History Interview, March 15, 2013 [PDF]
, 2013 Major Topics Covered: Overview of breast medical oncology: as a field; history of at MD Anderson Service to organizations and projects in the United States and abroad Views on MD Anderson presidentshttps://openworks.mdanderson.org ...
Hortobagyi, Gabriel N., MD +1 more
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