Results 101 to 110 of about 541,611 (331)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Protective effects of chlorogenic acid against glyphosate-induced organ and blood toxicity in Wistar rats

Arhiv za Higijenu Rada i Toksikologiju
Glyphosate, a widely used herbicide against broadleaf weeds and grasses, has been associated with various harmful effects. Our study examines the efficacy of chlorogenic acid (CGA) in alleviating the toxicity of a glyphosate-based herbicide (GBH) in 42 ...
Türkmen Ruhi, Birdane Yavuz Osman, Atik Orkun, Demirel Hasan Huseyin, Baser Durmus Fatih   +4 more
doaj   +1 more source

Antitumoral Effect of Syringe Acid on DU-145 Prostate Cancer Cells

Recent Trends in Pharmacology
Amaç: Prostat kanseri (PC), dünya çapında erkeklerde kanserden ölümlerin en yaygın nedenlerinden biridir ve PC'yi tedavi etmek için yeni ilaçlar halen geliştirilmektedir.
Sıdıka Genç, Yeşim Yeni
doaj   +1 more source

Hybrid Scaffolds Decouple Biochemical & Biophysical Regulation of Cell Phenotype

Advanced Healthcare Materials, EarlyView.
Replicating tissue‐specific extracellular matrix is crucial for understanding its role in disease. This work demonstrates independent control over stiffness, composition and 3D collagen architecture using hybrid scaffolds: patterned collagen perfused with defined hydrogels.
Xinyuan Song, Samantha C. Mitchell, Abbie N. Smart, William Hardiman, Daniel V. Bax, Ceri E. Staley, Catherine Probert, Pamela Collier, Marian Meakin, Alison A. Ritchie, Tania Mendonca, Amanda J. Wright, Victoria James, Anna M. Grabowska, Catherine L. R. Merry, Serena M. Best, Ruth E. Cameron, Jennifer C. Ashworth   +17 more
wiley   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Spontaneous senescence in the MDA‐MB‐231 cell line [PDF]

, 2006
Andrea Ćukušić, Milena Ivanković, Nikolina Škrobot, Marina Ferenac, Ivana Gotić, Mario Matijašić, Denis Polančec, Ivica Rubelj   +7 more
openalex   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

Oxidative stress/lipid peroxidation and antioxidant enzymes in apparently healthy individuals involved in physical exercise

Asian Journal of Medical Sciences, 2016
Background: Normal metabolic functions generate highly reactive compounds called free radicals in the body. Exercise is accompanied by increased oxygen consumption and enhanced Reactive Oxygen Species (ROS)/free radical production in humans.
Ikekpeazu Joy Ebele
doaj   +1 more source

Minocycline impairs TNF-α-induced cell fusion of M13SV1-Cre cells with MDA-MB-435-pFDR1 cells by suppressing NF-κB transcriptional activity and its induction of target-gene expression of fusion-relevant factors [PDF]

, 2019
Julian Weiler, Thomas Dittmar
openalex   +1 more source

National Comprehensive Trachoma Treatment Campaign: Community Monitoring of Mass Drug Administration (MDA) Coverage and Practices

, 2022
Hassan Abdulwahab Al-Shamahy
openalex   +1 more source