Results 111 to 120 of about 384,184 (313)

The Curative Activity of Isolated Fraction from Spathodea campanulata Beauv Stem Bark on Rat’s Exposed to Benzopyrene

Journal of Tropical Life Science, 2014
This paper reports a screening results of the secondary metabolites composed in Spathodea campanulata Beauv stem bark, evaluate inhibiting activity of malondialdehyde (MDA) on rat’s cancer model exposed with benzopyrene, and ...
Masruri Masruri, Mohamad Lutfillah, Ady Sumaryanto, Rurini Retnowati, Aulanni'am Aulanni'am   +4 more
doaj  

An Approach to Classification of MDA Tools

Pēdējā laikā ir parādījies pietiekami plašs rīku klāsts, kas atbalsta ideju par programmatūras izstrādes procesa bagātināšanu ar modelēšanas principiem; tātad, programmatūras kods tiek iegūts no sistēmas modeļa.
Čerņičkins, Antons, Ņikiforova, Oksana   +1 more
core  

Estetika Interaksi: Pendekatan MDA pada Game Nitiki [PDF]

, 2015
Rekonstruksi ragam hias batik dalam game merupakan proses kreatif mereka-ulang visual yang tertera pada kain batik ke dalam media digital yang bersifat interaktif.
Chandra, Tresnadi, AGUS, SACHARI
core  

MDA-MB-231 cellular fitness and migration in standard DMEM/F-12 medium with different serum concentrations in comparison with serum-free growth medium UC.

, 2018
(A) Viability of MDA-MB-231 cells in chemoattractant-free medium. (B) Cell speed of MDA-MB-231 cells in chemoattractant-free medium. (C) Forward migration indices in direction of the gradient (FMIII) and (D) perpendicular to the gradient (FMI┴) of MDA-MB-
Martina Häckl (5746043), Johannes Jürschick (5746040), Christopher Battle (1439731), Verena Biswenger (5746034), Jan Schwarz (5746046), Elias Horn (5746049), Roman Zantl (5746052), Nina Baumann (5746037)   +7 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Effect of Low-Level Laser Therapy on the Nrf2/Keap1 Pathway in NMRI Mice with Testicular Torsion [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Testicular torsion (TT) is a urological emergency characterized by twisting of the spermatic cord, which reduces blood flow and leads to testicular ischemia.
Mohammad Bayat, Mahsa Soltani, Roohollah Torabi, maryam baazm, Mitra Barzroodi   +4 more
doaj  

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source

Investigation of the Relationship between Antioxidant Levels and Body Mass Index and Obesity

Pharmata
Objective: Today, it is well known that obesity plays a role in the pathogenesis of many diseases, and one of these mechanisms of action is oxidative stress.
Nurcan Kılıç Baygutalp, Özgür Araz, Ufuk Uzun, İlayda Havuz, Neslihan Yüce, Mehlika Alataş, Fatmagül Düzenli, Elif Zeynep Öztürk   +7 more
doaj   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source