Results 81 to 90 of about 737,646 (322)
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Siberian Journal of Life Sciences and Agriculture, 2021 Green leafy kale (Brassica oleracea var. sabellica) has huge scientific attention because of its health-promoting functionality. In the present study the impact of NPK, energen, biostim and humate on flavonoid, phenolic compounds, vitamin C, carotenoids,
Joyce D. Anteh +2 more
doaj +1 more source
Hypoxia regulates stemness of breast cancer MDA-MB-231 cells
Medical Oncology, 2016 Human breast cancers include cancer stem cell populations as well as non-tumorigenic cancer cells. Breast cancer stem cells possess self-renewal capability and thus are the root cause of recurrence and metastasis of malignant tumors.
Jing Xie +5 more
semanticscholar +1 more source
Extension of Petri Nets by Aspects to Apply the Model Driven Architecture Approach [PDF]
, 2005 Within MDA models are usually created in the UML. However, one may prefer to\ud use different notations such as Petri-nets, for example, for modelling concurrency\ud and synchronization properties of systems. This paper claims that techniques that\ud are
Aksit, M., Roubtsova, E.E.
core +1 more source
An Assessment of Gypsy Moth Eradication Attempts in Michigan (Lepidoptera: Lymantriidae) [PDF]
, 2017 Michigan\u27s infestation of gypsy moth, Lymantria dispar, extends over 600,000 acres, First discovered in Michigan in the 19505, gypsy moth was reportedly eradicated through the use of DDT then reintroduced in the 1970s, Substantial circumstantial ...
Dreistadt, Steve H
core +3 more sources
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Frontiers in Health ServicesIntroductionSpinal muscular atrophy (SMA) is a rare disease characterized by challenges in its management both for patients and parents/caregivers. In Greece, these challenges are exacerbated by the lack of an integrated SMA patient pathway.
Kyriakos Souliotis +8 more
doaj +1 more source
Model Transformation with ATL into MDA from CIM to PIM Structured through MVC
ANT/SEIT, 2016 Models transformation is the most important key in Model Driven Architecture (MDA). The first transformation in MDA is Computing Independent Model (CIM) to Platform Independent Model (PIM) transformation, the second is PIM to Platform Specific Model (PSM)
Yassine Rhazali +2 more
semanticscholar +1 more source
Challenges in mass drug administration for treating lymphatic filariasis in Papua, Indonesia. [PDF]
, 2010 : BACKGROUND: The World Health Organization (WHO) Global Program to Eliminate Lymphatic Filariasis relies on mass drug administration (MDA) of two drugs annually for 4 to 6 years.
Bhullar, Navneet, Maikere, Jacob
core +3 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source