Results 61 to 70 of about 384,184 (313)

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Caring for children with spinal muscular atrophy in Greece: parents' and caregivers' experience with the healthcare system

Frontiers in Health Services
IntroductionSpinal muscular atrophy (SMA) is a rare disease characterized by challenges in its management both for patients and parents/caregivers. In Greece, these challenges are exacerbated by the lack of an integrated SMA patient pathway.
Kyriakos Souliotis, Kyriakos Souliotis, Christina Golna, Chara Tzavara, Christiana Vasileiadi, Pavlos Golnas, Aikaterini Ntokou, Kornilia Binou, Antigone Karras   +8 more
doaj   +1 more source

Strategies for Improving MDA-Based Development Processes

, 2010
The Model Driven Architecture (MDA) is meant to facilitate system development by using models for representing both the "problem" and its "solution". In its ideal form, software development based on MDA would follow a development process that begins by ...
Mehdi Fahmideh Gholami, Ramsin, Raman, Raman Ramsin, Gholami, Mehdi Fahmideh   +3 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Redox and essential metal status in the brain of Wistar rats acutely exposed to a cadmium and lead mixture

Arhiv za Higijenu Rada i Toksikologiju, 2020
Most Pb and Cd neurotoxicity studies investigate exposure to either of the toxic metals alone, while data on co-exposure are scarce. The aim of our study was to fill that gap by investigating acute combined effects of Pb and Cd on redox and essential ...
Javorac Dragana, Đorđević Aleksandra Buha, Anđelković Milena, Tatović Simona, Baralić Katarina, Antonijević Evica, Kotur-Stevuljević Jelena, Đukić-Ćosić Danijela, Antonijević Biljana, Bulat Zorica   +9 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Changes in lipid peroxidation, glutathione and fertility in tuj sheep after combined administration of vitamin a and e and passive immunization with testosterone antibodies [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017
This study investigated the effect of testosterone antibodies and a combination of vitamin A and E on reproductive performance and lipid peroxidation in Tuj sheep during the oestrus period.
KAMİLOĞLU NN, KAÇAR C, GÜVEN A, YILDIZ B, KURU M, KAYA S, EROĞLU HA, KOÇ E   +7 more
doaj   +1 more source

MDA-MB-231_ONTARGETPlus_GEFGAP screen (Data Record 4).xlsx

, 2017
Raw data for the ONTARGETPlus RhoGEF and RhoGAP RNAi screen on MDA-MB-231 ...
Chris Bakal (192137), Patricia Pascual Vargas (2925483), Julia Sero (2925480), Vicky Bousgouni (595380), Sam Cooper (2925486), Mar Arias-Garcia (2925477), Springer Nature Admin (428815)   +6 more
core   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

A New Algorithm of MDA-OR

Behaviormetrika, 1978
Dr. Hayashi developed one of methods for multidimensional scaling problem, named MDA. This method is a very useful one, but its computation is very difficult. In the present paper, the author shows a modification of its computation with some numerical examples in one dimensional case.
openaire   +1 more source