Results 41 to 50 of about 458,494 (300)

The importance of patient compliance in repeated rounds of mass drug administration (MDA) for the elimination of intestinal helminth transmission

Parasites & Vectors, 2017
BackgroundSystematic non-compliance to chemotherapeutic treatment among a portion of the eligible population is thought to be a major obstacle to the elimination of helminth infections by mass drug administration (MDA).
Sam H. Farrell, J. Truscott, R. Anderson
semanticscholar   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Biological corridors are crucial habitat features that boost biodiversity in agroecological systems of Argentina

Ecological Solutions and Evidence
The implementation of biological corridors in agroecosystems is a management strategy to increase biodiversity and create habitats for beneficial species that help reestablish biological and natural control by improving the complexity of trophic networks
Paula Taraborelli, Micaela Malaspina, Natalia Carrasco, Andrea Scavone, Alejandra López   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Induction of G1-phase cell cycle arrest and apoptosis pathway in MDA-MB-231 human breast cancer cells by sulfated polysaccharide extracted from Laurencia papillosa

Cancer Cell International, 2016
Marine algae consumption is linked to law cancer incidences in countries that traditionally consume marine products. Hence, Phytochemicals are considered as potential chemo-preventive and chemotherapeutic agents against cancer.
Hossam Murad, Mohammad Hawat, Adnan M. Ekhtiar, Abdulmunim Aljapawe, A. Abbas, Hussein Darwish, Oula Sbenati, A. Ghannam   +7 more
semanticscholar   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Non-destructive determination of Malondialdehyde (MDA) distribution in oilseed rape leaves by laboratory scale NIR hyperspectral imaging

Scientific Reports, 2016
The feasibility of hyperspectral imaging with 400–1000 nm was investigated to detect malondialdehyde (MDA) content in oilseed rape leaves under herbicide stress.
Wenwen Kong, Fei Liu, Chu Zhang, Jianfeng Zhang, Hailin Feng   +4 more
semanticscholar   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Antidiabetic Potentials of Button Mushroom (Agaricus bisporus) on Alloxan-Induced Diabetic Rats

Biosaintifika: Journal of Biology & Biology Education, 2018
Button mushrooms (Agaricus bisporus) is an edible mushroom that is most widely cultivated in the world. It contains bioactive compounds that might provide beneficial effects on diabetes mellitus patient.
Nuraeni Ekowati, Nilasari Indah Yuniati, Hernayanti Hernayanti, Nuniek Ina Ratnaningtyas   +3 more
doaj   +1 more source

Mitigation of the negative effect of auxinic herbicide by bacterial suspension of Pseudomonas protegens DA1.2 in wheat plants under drought conditions

Acta Agriculturae Slovenica, 2023
Effect of auxin-producing bacterial strain (Pseudomonas protegens DA1.2) was investigated under conditions of drought and herbicide treatment in wheat plants.
Sergey СHETVERIKOV, Arina FEOKTISTOVA, Maxim TIMERGALIN, Timur RAMEEV, Gaisar HKUDAYGULOV, Aliya KENDJIEVA, Margarita BAKAEVA, Darya СHETVERIKOVA, Sergey STARIKOV, Danil SHARIPOV   +9 more
doaj   +1 more source