Results 51 to 60 of about 458,494 (300)
Tropical Medicine and Health, 2014 Lymphatic filariasis is one of the neglected tropical diseases. It is estimated that 120 million people are currently infected in 73 countries where filariasis is endemic. Lymphatic filariasis is a leading cause of chronic disability worldwide, including of 15 million people who have lymphoedema (elephantiasis) and 25 million men who have hydrocoele.
openaire +3 more sources
Determinants of MDA impact and designing MDAs towards malaria elimination
eLife, 2020 Malaria remains at the forefront of scientific research and global political and funding agendas. Malaria models have consistently oversimplified how mass interventions are implemented. Here, we present an individual based, spatially explicit model of P.
Gao, B +5 more
openaire +5 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Role of Pre-Sowing Gamma-Irradiation of Seeds in the Salt-Resistance of Phaseolus vulgaris L. [PDF]
Journal of Stress Physiology & Biochemistry, 2020 Studies of the effect of low-dose γ-radiation on the resistance of plants to abiotic stresses have recently attracted great attention of researchers due to the constant environmental degradation. In separate examples, it was shown that γ-radiation in low
E.S. Jafarov +4 more
doaj
Journal of Family Medicine and Primary Care, 2023 Background: Despite annual rounds of mass drug administration (MDA) being carried out every year since 2004 to break the transmission of lymphatic filariasis, India has not achieved elimination status in many areas of country. This study was conducted to
Dhananjay Kumar +4 more
doaj +1 more source
Metabolic changes associated with methionine stress sensitivity in MDA-MB-468 breast cancer cells
Cancer & Metabolism, 2016 The majority of cancer cells have a unique metabolic requirement for methionine that is not observed in normal, non-tumorigenic cells. This phenotype is described as “methionine dependence” or “methionine stress sensitivity” in which cancer cells are ...
Stacey L. Borrego +11 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Model Transformation with ATL into MDA from CIM to PIM Structured through MVC
ANT/SEIT, 2016 Models transformation is the most important key in Model Driven Architecture (MDA). The first transformation in MDA is Computing Independent Model (CIM) to Platform Independent Model (PIM) transformation, the second is PIM to Platform Specific Model (PSM)
Yassine Rhazali +2 more
semanticscholar +1 more source