Results 51 to 60 of about 5,869 (296)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Additional psychometric data for the Spanish Modified Dental Anxiety Scale, and psychometric data for a Spanish version of the Revised Dental Beliefs Survey

BMC Oral Health, 2010
Background Hispanics comprise the largest ethnic minority group in the United States. Previous work with the Spanish Modified Dental Anxiety Scale (MDAS) yielded good validity, but lower test-retest reliability.
Weinstein Philip, Farjo Nadia, Hillstead M Blake, Coolidge Trilby, Coldwell Susan E   +4 more
doaj   +1 more source

‘Maisons Des Adolescents’, Youth Mental Health in France

European Psychiatry, 2022
Since 1999, more than 100 “Maisons des Adolescents” (MDAs) - “House of Adolescents” - have been developed in France. These integrated youth-friendly facilities enabled young persons to gain access to specific care.
L. Benoit
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Characterization, epidemiology and risk factors of multiple drug allergy syndrome and multiple drug intolerance syndrome: A systematic review

Clinical and Translational Allergy, 2022
Background Multiple drug allergy and multiple drug intolerance syndrome (MDAS/MDIS) labels are an impediment to clinical care and knowledge regarding these conditions is limited.
Parbir K. Jagpal, Saad Alshareef, John F. Marriott, Mamidipudi Thirumala Krishna   +3 more
doaj   +1 more source

Drug regimen for MDAs and treatment of scabies.

, 2015
Drug regimen for MDAs and treatment of scabies.
Deborah C. Holt (216351), Leanne Bundhala (820478), Mark Chatfield (64494), Ross M. Andrews (256798), Roslyn Gundjirryirr (820477), Jennifer Shield (820476), Richard Speare (184539), Thérèse M. Kearns (820474), Wendy Page (820475), Jonathan R. Carapetis (256810), Bart J. Currie (131288), Allen C. Cheng (236183), Eddie Mulholland (820479), James McCarthy (243966)   +13 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Reliability and Validity of the Modified Dental Anxiety Scale Among Children Aged 9 to 12 Years

Dentistry Journal
Objectives: Our aim was to study whether the Modified Dental Anxiety Scale (MDAS) is reliable and valid for use in children aged 9 to 12 years. Methods: The study population was a convenient sample of Finnish comprehensive school pupils in the third and ...
Satu Lahti, Mika Kajita, Vesa Pohjola, Auli Suominen   +3 more
doaj   +1 more source

Assessing "First Mile" Supply Chain Factors Affecting Timeliness of School-Based Deworming Interventions: Supply and Logistics Performance Indicators.

PLoS Neglected Tropical Diseases, 2015
BackgroundBetween 2007 and 2012, Children Without Worms (CWW) oversaw the Johnson & Johnson (J&J) donation of Vermox (mebendazole) for treatment of school-age children to control soil-transmitted helminthiasis (STH).
Kimberly M Koporc, Eric Strunz, Cassandra Holloway, David G Addiss, William Lin   +4 more
doaj   +1 more source

Simulated influenza transmission dynamics under combined control measures assuming no MDAs.

, 2023
Simulated influenza transmission dynamics under combined control measures assuming no MDAs.
Wendy Beauvais (4836825), Darryl Ragland (397872), Eric Kontowicz (12225304), Max Moreno-Madriñan (15411739)   +3 more
core   +1 more source