Results 61 to 70 of about 5,869 (296)

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Genetic Landscape of Müllerian Duct Anomalies: A Comprehensive Review

open access: yesReproductive Medicine and Biology
Background Müllerian duct anomalies (MDAs) are developmental malformations of the female genital tract that present as a series of abnormalities within the reproductive tracts of females.
Lin He   +6 more
doaj   +1 more source

Overall effect of direct and indirect interactions on enrichment of experimentally validated MDAs.

open access: yes, 2015
(A) Increasing the number miRNA-targeted DG enrichments for true MDAs in the whole set of putative MDAs. (B) Comparably, higher PIS value only slightly enriches for true MDAs.
Xiaodan Chu (785721)   +10 more
core   +1 more source

Some psychometric properties of the Chinese version of the Modified Dental Anxiety Scale with cross validation

open access: yesHealth and Quality of Life Outcomes, 2008
Objective To assess the factorial structure and construct validity for the Chinese version of the Modified Dental Anxiety Scale (MDAS). Materials and methods A cross-sectional survey was conducted in March 2006 from adults in the Beijing area.
Lahti Satu   +4 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij   +11 more
wiley   +1 more source

Biomimetic Core–Shell Liposome Nanoparticles Deplete Lipoproteins and Enhance the Purity of Extracellular Vesicles from Human Blood

open access: yesAdvanced Functional Materials, EarlyView.
Lipoprotein‐mimicking nanoparticles (SL‐NPs), comprising Fe3O4@SiO2 cores coated with liposomal bilayers, selectively capture lipoproteins through protein corona formation. The resulting SL‐NP‐lipoprotein complexes can be removed by low‐speed centrifugation, thereby enhancing the purity of small extracellular vesicles (sEVs) isolated from human serum ...
Man‐Di Wang   +7 more
wiley   +1 more source

Translation and validation of modified dental anxiety scale based on adult Taiwan population

open access: yesBMC Oral Health, 2021
Background Dental anxiety is associated with negative experiences of dental treatment and dental-visiting behavior. The Modified Dental Anxiety Scale (MDAS) is widely used for assessing dental anxiety.
Chia-Shu Lin   +6 more
doaj   +1 more source

A New Algorithm of MDA-OR

open access: yesBehaviormetrika, 1978
Dr. Hayashi developed one of methods for multidimensional scaling problem, named MDA. This method is a very useful one, but its computation is very difficult. In the present paper, the author shows a modification of its computation with some numerical examples in one dimensional case.
openaire   +1 more source

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