Results 101 to 110 of about 22,143,644 (312)

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

open access: yesAdvanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta   +14 more
wiley   +1 more source

Effectiveness of a thoracic multidisciplinary clinic in the treatment of stage III non-small-cell lung cancer

open access: yesJournal of Multidisciplinary Healthcare, 2016
Eliot L Friedman,1 Robert J Kruklitis,2 Brian J Patson,1 Dennis M Sopka,3 Michael J Weiss4 1Division of Hematology-Medical Oncology, 2Division of Pulmonary and Critical Care Medicine, 3Department of Radiation Oncology, 4Health Systems Research and ...
Friedman EL   +4 more
doaj  

Automatic alignment of hieroglyphs and transliteration [PDF]

open access: yes, 2011
Automatic alignment has important applications in philology, facilitating study of texts on the basis of electronic resources produced by different scholars.
Nederhof, Mark Jan
core  

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

open access: yesAdvanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen   +9 more
wiley   +1 more source

Platelet concentrates modulate myeloid dendritic cell immune responses

open access: yesPlatelets, 2018
Platelet transfusion has been reported to modulate the recipients’ immune system. To date, the precise mechanism(s) driving poor patient outcomes (e.g., increased rate of mortality, morbidity, infectious complications and prolonged hospital stays ...
Katrina K. Ki   +3 more
doaj   +1 more source

Caracterización física de ligantes asfálticos con CECABASE para mezclas tibias [PDF]

open access: yes, 2013
Reducir el consumo de energía así como las emisiones en la industria de la producción de mezclas asfálticas requiere la reducción de temperaturas de fabricación, las cuales tienden a perjudicar el rendimiento de la misma, por tal motivo el objetivo de ...
Casanova Torres, Sandra Lorena   +1 more
core  

Accelerating Biosensor Discovery: A Computationally‐Driven Pipeline for Microplastics Monitoring

open access: yesAdvanced Intelligent Discovery, EarlyView.
A computationally guided pipeline unites molecular simulation, synthetic biology, electrochemical engineering, and machine learning to accelerate biosensor discovery. A Bacillus anthracis carbohydrate‐binding module is used to develop a high‐performance micro‐ and nanoplastics sensor with greatly reduced error and variability.
Gabriel X. Pereira   +13 more
wiley   +1 more source

Construção de conhecimentos matemáticos através da utilização de peças LEGO

open access: yesREMAT, 2016
Por sua semelhança com o método de resolução, o qual geralmente nos leva à fatoração como mecanismo de solução, o presente trabalho teve como objetivo traçar reflexões acerca do mínimo múltiplo comum (MMC) e máximo divisor comum (MDC).
Vinícius Borovoy Sant'ana   +2 more
doaj   +3 more sources

A Generalizable Transformer Framework for Gene Regulatory Network Inference from Single‐Cell Transcriptomes

open access: yesAdvanced Intelligent Systems, EarlyView.
FTGRN introduces an LLM‐enhanced framework for gene regulatory network inference through a two‐stage workflow. It combines a Transformer‐based model, pretrained on GPT‐4 derived gene embeddings and regulatory knowledge, with a fine‐tuning stage utilizing single‐cell RNA‐seq data.
Guangzheng Weng   +7 more
wiley   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

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