Results 131 to 140 of about 22,143,644 (312)

MACHOs as brown dwarfs [PDF]

, 1998
Recent observations of microlensing events in the Large Magellanic Cloud suggest that a sizable fraction of the galactic halo is in the form of Massive Astrophysical Compact Halo Objects (MACHOs). Although the average MACHO mass is presently poorly known,
De Paolis, F., Ingrosso, G., Jetzer, Ph., Roncadelli, M.   +3 more
core   +2 more sources

Organ‐sparing strategies in patients with MSI/dMMR tumors including Lynch syndrome: Current state of the art and future perspectives for clinical decision‐making

International Journal of Cancer, EarlyView.
Abstract Deficiency in DNA mismatch repair (dMMR) is a common pathway of carcinogenesis across different tumor types and confers a characteristic microsatellite instability‐high (MSI‐H) molecular phenotype. The MSI‐H/dMMR phenotype may arise from an inherited pathogenic variant in the context of Lynch syndrome and is most frequently observed in ...
Martin Duval, Antoine Dardenne, Thomas Samaille, Leo Mas, Jérémie H. Lefèvre, Xavier Dray, Mathilde Wagner, Romain Cohen, Thierry André   +8 more
wiley   +1 more source

Inter- and intra-examiner reliability of short-term measurement of heart rate variability on rest in patients hospitalized with COVID-19

Scientific Reports
Measures reflecting cardiac sympathovagal activity, particularly those associated with heart rate variability (HRV), are widely recognized and utilized in both scientific and clinical contexts.
Aldair Darlan Santos-de-Araújo, Murilo Rezende Oliveira, André Pontes-Silva, Laise Nunes Rodrigues, Cyrene Piazera Silva Costa, Renan Shida Marinho, Sigrid de Sousa dos Santos, Ross Arena, Shane A. Phillips, Daniela Bassi-Dibai, Audrey Borghi-Silva   +10 more
doaj   +1 more source

Comparación de módulos dinámicos de probetas elaboradas por el método Marshall y por el método Superpave [PDF]

, 2007
En el mundo se han emprendido grandes campañas para mejorar el comportamiento de las mezclas asfálticas; entre ellas, está la liderada por los Estados Unidos denominado 'Programa estratégico de investigación en carreteras (SHRP)' en la que se ...
Guzmán Meléndez, María Rosa, Marín Uribe, Carlos Rodolfo   +1 more
core   +1 more source

Early matrine intervention of gut microbiota for type 2 diabetes prevention

iMetaOmics, EarlyView.
How matrine influences gut microbiota imbalance to prevent the progression of diabetes remains unclear. We conduct experiments using mice to simulate the stages of diabetes development and matrine intervention. Combined with amplicon sequencing, we find that the gut microbiota of diabetic mice continuously changes with the progression of the disease ...
Zhexue Sun, Hujie Lyu, Hailang Xu, Xianjin Qin, Wei Li   +4 more
wiley   +1 more source

Implementation of a mixed-methods heat acclimation programme in a professional soccer referee before the 2022 FIFA world cup in Qatar: a case study

BMJ Open Sport & Exercise Medicine
Objectives This case study reports the real-world practicalities of implementing a mixed-methods heat acclimation (HA) programme before the 2022 FIFA World Cup.Methods One male English soccer referee (age: 44 years; height: 1.82 m; body mass: 76.0 kg ...
Dale B Read, Daniel T Evans, Simon Breivik, Joshua D Elliott, Oliver R Gibson, Laurence P Birdsey   +5 more
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Clinical relevance of double‐arm blood pressure measurement and prevalence of clinically important inter‐arm blood pressure differences in Indian Primary Care

The Journal of Clinical Hypertension, Accepted Article., 2022
Abstract Hypertension guidelines recommend measuring blood pressure (BP) in both arms at least once. However, this is seldom done due to uncertainties regarding measurement procedure and the implications of finding a clinically important inter‐arm BP difference (IAD).
Gurpreet S. Wander, Sinead T.J. McDonagh, M. Srinivasa Rao, R. Alagesan, JC Mohan, Ajit Bhagwat, AK Pancholia, M. Viswanathan, Manoj Bhavrilal Chopda, A Purnanand, PLN kapardhi, Arun R Vadavi, R Selvaraj, Pankaj Aneja, Suhas Hardas, Neil Bordoloi, N Sivakadaksham, Christopher E goswami, Christopher E Clark, Willem J. Verberk   +19 more
wiley   +1 more source

Single-cell resolution characterization of myeloid-derived cell states with implication in cancer outcome

Nature Communications
Tumor-associated myeloid-derived cells (MDCs) significantly impact cancer prognosis and treatment responses due to their remarkable plasticity and tumorigenic behaviors.
Gabriela Rapozo Guimarães, Giovanna Resk Maklouf, Cristiane Esteves Teixeira, Leandro de Oliveira Santos, Nayara Gusmão Tessarollo, Nayara Evelin de Toledo, Alessandra Freitas Serain, Cristóvão Antunes de Lanna, Marco Antônio Pretti, Jéssica Gonçalves Vieira da Cruz, Marcelo Falchetti, Mylla M. Dimas, Igor Salerno Filgueiras, Otavio Cabral-Marques, Rodrigo Nalio Ramos, Fabiane Carvalho de Macedo, Fabiana Resende Rodrigues, Nina Carrossini Bastos, Jesse Lopes da Silva, Edroaldo Lummertz da Rocha, Cláudia Bessa Pereira Chaves, Andreia Cristina de Melo, Pedro M. M. Moraes-Vieira, Marcelo A. Mori, Mariana Boroni   +24 more
doaj   +1 more source

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner, Amit Assa, Mikkel Malham, Shira Yuval Bar‐Asher, Carla Rayan, Jeffrey S. Hyams, Holm H. Uhlig, Brad Pasternak, David C. Wilson, Hilary K. Michel, Lissy de Ridder, Eric Zuckerman, Marina Aloi, Peter Szitanyi, Marla C. Dubinsky, Anne M. Griffiths, Roberto Saldana, Javier Martín‐de‐Carpi, Eytan Wine, Richard K. Russell, Jeremy Adler, Joseph Picoraro   +21 more
wiley   +1 more source