Results 91 to 100 of about 1,892 (112)

EGFRvIII-positive glioblastoma contributes to immune escape and malignant progression via the c-Fos-MDK-LRP1 axis

Cell Death and Disease
Epidermal growth factor receptor variant III (EGFRvIII) confers growth advantage to glioblastoma multiforme (GBM) and is associated with significantly shorter survival in GBM patients.
Feng Yuan, Yingshuai Wang, Lei Yuan, Ting Tang, Lei Ye, Yan Li, Xingliang Dai, Hongwei Cheng   +7 more
semanticscholar   +1 more source

Multi-Step Deep Koopman Network (MDK-Net) for Vehicle Control in Frenet Frame

IEEE/RJS International Conference on Intelligent RObots and Systems
The highly nonlinear dynamics of vehicles present a major challenge for the practical implementation of optimal control and Model Predictive Control (MPC) approaches in path planning and tracking applications.
Mohammad Abtahi, Mahdis Rabbani, Armin Abdolmohammadi, S. Nazari   +3 more
semanticscholar   +1 more source

Ugonin P mitigates osteolytic bone metastasis by suppressing MDK via upregulating miR-223-3p expression

International Journal on Biological Sciences
Bone metastasis is a significant complication in advanced-stage cancers, especially breast and lung malignancies, profoundly influencing prognosis and quality of life. Osteolytic bone metastasis contains multiple interactions between cancer cells and the
Yat-Yin Law, Haritha Rengamanar, Chih-Ying Wu, Chih-Chuang Liaw, S. S. Ghule, Yu-Ying Wu, Kuan-Ying Lai, Le Huynh Hoai Thuong, Trung-Loc Ho, Athena Yanjen Lin, Y. Fong, Chun-Hao Tsai, Chih-Hsin Tang   +12 more
semanticscholar   +1 more source

Prognostic relevance of MDK and TIMP1 with immune infiltration in lung adenocarcinoma.

International Archives of Allergy and Immunology
BACKGROUND LUAD is a common and fatal form of lung cancer, with varying expressions of MDK and TIMP1 across different cancers. However, their specific roles in LUAD progression and tumor immunity remain unclear.
Qinghua Zhu, Qingqing Huang, Xiaohua He, Miaomiao Jiang, Junkai Fu, Chenyuan Ding   +5 more
semanticscholar   +1 more source

Metabolic reprogramming of arachidonic acid in clear cell renal carcinoma promotes an immunosuppressive microenvironment by activating MDK signaling pathway

Clinical and Experimental Medicine (Testo stampato)
Metabolic reprogramming is a key feature of clear cell renal cell carcinoma (ccRCC), and metabolic abnormality can lead to significant changes in gene expression, resulting in the immunosuppressive microenvironment.
Jiaxi Yao, Tong Xu, Chenyuan Wang, Junfeng Xie, Qing Jiang   +4 more
semanticscholar   +1 more source

Abstract LB435: Novel MDK targeted therapy for treating triple negative breast cancer

Cancer Research
Triple-negative breast cancer (TNBC) is an aggressive and heterogeneous subtype of breast cancer with poor clinical outcome. Current therapies are not effective as TNBC tend to develop resistant to treatment.
Megharani Mahajan, Alondra L Rodriguez Sanchez, Sridharan Jayamohan, Jessica D. Johnson, John R Sanchez, Panneerdoss Subbarayalu, M. Rao, Ratna K. Vadlamudi, Gangadhara R. Sareddy, H. Nair, S. Viswanadhapalli   +10 more
semanticscholar   +1 more source

Analysis of Expression Levels and Functions of MDK and PTN Genes in Colorectal Cancer

, 2022
Purpose Colorectal cancer (CRC) is the third most common and the fourth most lethal type of cancer. Current therapies for CRC mainly include chemotherapy, radiotherapy, and surgery.
Feng Jiang, Huilian Huang, Yang Liu
semanticscholar   +1 more source

Remote neuromuscular electrical stimulation upregulates MDK to enhance macrophage efferocytosis via LRP1 in wound healing.

Journal of Biomedical Research
Neuromuscular electrical stimulation (NMES) is a well-established therapeutic approach for chronic wounds. Conventionally, NMES involves direct electrode contact with wounds or adjacent healthy skin; however, it is limited by the need for wound exposure ...
Lijuan Zong, Chong Liu, Li Zhang, Xueyou Tao, Qingyan Tian, Xiaokai Zhou, Yu Wang, Na Shen, Jiaming Gong, Qingyuan Zhuang, Tong Wang, Wentao Liu, Ying Shen, Liang Hu   +13 more
semanticscholar   +1 more source

RGS16-driven cancer-associated fibroblasts promote esophageal squamous cell carcinoma progression via the MDK-SDC1 axis-mediated intercellular crosstalk

Biology Direct
Cancer-associated fibroblasts (CAFs) are critical components of the tumor microenvironment (TME) and have important roles in carcinogenesis and metastasis by facilitating cancer cell proliferation, angiogenesis, extracellular matrix (ECM) remodeling, and
Di Wu, Mingzhi Cao, Changgang Yang, Wanshun Li, Deyu Zhang, Shihua Yao, Hong Yu, Gengxi Jiang   +7 more
semanticscholar   +1 more source

HEMATOLOGICAL PROFILE OF LARGE YOUTH CATTLE WHEN FEEDING THE FEED ADDITIVE “MDK”

SCIENTIFIC SUPPORT FOR LIVESTOCK BREEDING IN SIBERIA
The blood system is one of the most dynamic systems of the body. The purpose of our research was to study the effect of the feed additive “MDK” on the hematological parameters of the blood of young cattle.
A. Kozinec, M. Nadarinskaya, T. Kozinec, O. Golushko, M. Grin', S. Kovaleva   +5 more
semanticscholar   +1 more source