Results 121 to 130 of about 40,945 (273)

First study of safety and tolerability of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in patients with alcohol use disorder: preliminary data on the first four participants

open access: yesBMJ Case Reports, 2019
We present the preliminary data in an ongoing open-label safety and tolerability proof of concept study exploring the potential role for 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in treating patients with alcohol use disorder.
B. Sessa   +3 more
semanticscholar   +1 more source

Application of Wastewater‐Based Epidemiology in Japan to Estimate the Prevalence of Substance Use Including Methamphetamine and Ephedrine

open access: yesChemistry – An Asian Journal, Volume 21, Issue 3, 12 February 2026.
Methamphetamine was the only illicit drug consistently detected (consumption at 17.0 ± 5.1 mg/day/1000people). High levels of its precursors, ephedrine, and pseudoephedrine were likely from legal medicines, although there is a high risk of diversion.
Quyen T. T. Do   +4 more
wiley   +1 more source

Drug-drug interactions between psychiatric medications and MDMA or psilocybin: a systematic review

open access: yesPsychopharmacology, 2022
Aryan Sarparast   +3 more
semanticscholar   +1 more source

Metabolites of the ring-substituted stimulants MDMA, methylone and MDPV differentially affect human monoaminergic systems

open access: yesJournal of Psychopharmacology, 2019
Background: Amphetamine analogs with a 3,4-methylenedioxy ring-substitution are among the most popular illicit drugs of abuse, exerting stimulant and entactogenic effects.
D. Luethi   +8 more
semanticscholar   +1 more source

Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA

open access: yesCell Discovery, 2018
Heroin, nicotine, cocaine, and MDMA are abused by billions of people. They are believed to target midbrain dopamine neurons and/or serotonin neurons, but their effects on the dynamic neuronal activity remain unclear in behaving states.
Chao Wei   +6 more
semanticscholar   +1 more source

Surveillance of Phenibut in Wastewater During a Brazilian Carnival

open access: yesDrug Testing and Analysis, Volume 18, Issue 2, Page 192-197, February 2026.
This study reports the first detection of phenibut in Brazilian wastewater. Phenibut, a substance readily sold online to improve concentration, reaches wastewater treatment plants (WWTPs) after consumption by the population. Samples from WWTPs in the cities of Recife and Olinda in Northeastern Brazil were collected during the world's largest Carnival ...
Bruna R. de S. Gomes   +5 more
wiley   +1 more source

Closing Evidence Gaps on the Prevalence and Harms of New Psychoactive Substances in Scotland [PDF]

open access: yes, 2015
This paper considers the state of knowledge on New Psychoactive Substances (NPS) in Scotland, with a focus on prevalence and harms and puts forward proposals which may assist in closing existing evidence ...
Gillies, Allan
core  

Drug decriminalization and policy alienation among frontline police in British Columbia: A qualitative study

open access: yesCriminology &Public Policy, Volume 25, Issue 1, Page 63-88, February 2026.
Abstract Research Summary This qualitative study examines how frontline police officers in British Columbia experienced and adapted to Canada's first formal drug decriminalization policy 1 year after implementation. Drawing on 30 semi‐structured interviews and using thematic analysis with a policy alienation and street‐level bureaucracy lens, we ...
Sarah Ferencz   +2 more
wiley   +1 more source

Effects of Intravenous Ketamine on Posttraumatic Stress Disorder (PTSD): A Systematic Review

open access: yesActa Psychiatrica Scandinavica, Volume 153, Issue 2, Page 95-107, February 2026.
ABSTRACT Introduction Posttraumatic stress disorder (PTSD) is a mental disorder resulting from exposure to traumatic events. Evidence suggests that ketamine may be efficacious in treating PTSD, however, ketamine's mechanisms in treating PTSD remain unclear. Herein, this review aims to evaluate the clinical outcomes of ketamine treatment in persons with
Liyang Yin   +15 more
wiley   +1 more source

The Role of The A2A Receptor in Cell Apoptosis Caused by MDMA [PDF]

open access: yes, 2012
OBJECTIVE: Ecstasy, also known as 3, 4-methylenedioxymethamphetamine (MDMA), is a psychoactive recreational hallucinogenic substance and a major worldwide recreational drug.
Alizadeh, Akram.   +4 more
core   +2 more sources

Home - About - Disclaimer - Privacy