Results 171 to 180 of about 7,268 (227)

Disrupting the Undruggable: Emerging Modalities for Targeting Protein-Protein Interactions in Oncology. [PDF]

Biology (Basel)
El-Tanani M, Rabbani SA, Wali AF, El-Tanani Y, Sharma S.   +4 more
europepmc   +1 more source

Dual functionality of MDM2 in PROTACs expands the horizons of targeted protein degradation. [PDF]

Biomark Res
Zhao J, Chen H, Liang C.
europepmc   +1 more source

Special Issue "p53-Oncogene, Tumor Suppressor Gene, Guardian of the Genome and the Cell". [PDF]

Int J Mol Sci
Rangno D, Bozko P.
europepmc   +1 more source

Circadian rhythm lncRNA <i>NRON</i> is dysregulated in autism spectrum disorder: an observational study. [PDF]

Biochem Biophys Rep
Ziaei A, Shirvani-Farsani Z, Ghafouri-Fard S.   +2 more
europepmc   +1 more source

Recent Exploration of Right-Handed D-Sulfonyl-γ-AApeptides as Potential Tools Toward α-Helical Mimicry. [PDF]

Chempluschem
Fontaine J, Cai J.
europepmc   +1 more source

Engineering Protease-Resistant Peptides via Non-Canonical Amino Acids: Design Strategies and Biosynthetic Advances. [PDF]

Bioengineering (Basel)
Deng C, Fan Z, Xu Y, Cao M, Liao J, Meng M.   +5 more
europepmc   +1 more source

Insights into the host response to 'dormant' Mycobacterium tuberculosis utilizing 'Vitamin C-induced dormant Mtb' THP-1 cell infection model. [PDF]

BMC Genomics
Kumari K, Batra SD, Sikri K, Tyagi JS.
europepmc   +1 more source

Therapeutic peptides and their delivery using lipid-based nanoparticles. [PDF]

Tzu Chi Med J
Yen JH, Chang CC, Wu TY, Yang CH, Hsu HJ, Liou JW.   +5 more
europepmc   +1 more source

Autoinhibition of MDMX by Intramolecular p53 Mimicry [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2015
The p53 inhibitor MDMX is controlled by multiple stress signaling pathways. Using a proteolytic fragment release (PFR) assay, we detected an intramolecular interaction in MDMX that mechanistically mimics the interaction with p53, resulting in ...
Jiandong Chen, Ernst Schönbrunn, Wade Borcherds   +2 more
exaly   +5 more sources

MDMX Acts as a Pervasive Preleukemic-to-Acute Myeloid Leukemia Transition Mechanism [PDF]

Cancer Cell, 2021
MDMX is overexpressed in the vast majority of patients with acute myeloid leukemia (AML). We report that MDMX overexpression increases preleukemic stem cell (pre-LSC) number and competitive advantage.
Jidong Shan, Guillermina Lozano, Hiroki Gotō   +2 more
exaly   +2 more sources