Results 121 to 130 of about 159,394 (277)

Green synthesized Ag–Cu nanocomposites as an improved strategy to fight multidrug-resistant bacteria by inhibition of biofilm formation: In vitro and in silico assessment study

Green Processing and Synthesis
This study explores the green synthesis and characterization of monometallic Ag nanoparticles (NPs), Cu NPs, and bimetallic Ag–Cu NPs mediated by the aqueous extract of Syzygium aromaticum as a reducing agent.
Abbas Jafar Abdulkareem, Hasoon Buthenia Abd Alhamza, Jabir Majid Sakhi, Ghotekar Suresh, Swelum Ayman Abdel-Aziz   +4 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Survey on integron-mediated antimicrobial resistance genes among Escherichia coli and Klebsiella spp. multi-drug resistant clinical isolates [PDF]

مجله دانشگاه علوم پزشکی گیلان
Background Escherichia coli and Klebsiella spp. are amongst the most important causative agents of nosocomial and urinary tract infections. Integrons are genetic elements that carry genetic determinants for antimicrobial resistance and one of the ...
Marzie Taheripour Sisakht, Niloofar Boustani, Reza Khashei   +2 more
doaj  

Carbapenemase Producers Among Extensive Drug-Resistant Gram-Negative Pathogens Recovered from Febrile Neutrophilic Patients in Egypt

Infection and Drug Resistance, 2020
Samar S Mabrouk,1 Ghada R Abdellatif,1 Mona R El-Ansary,2 Khaled M Aboshanab,3 Yasser M Ragab4 1Department of Microbiology, Faculty of Pharmacy, Ahram Canadian University (ACU), 6th of October, Giza, Egypt; 2Department of Biochemistry, Modern University ...
Mabrouk S, Abdellatif G, El-Ansary M, Aboshanab K, Ragab Y   +4 more
doaj  

CD4 evolution over time in MDR-TB/HIV co-infected patients under ART and MDR-TB treatment, Mumbai, India.

, 2013
CD4 evolution over time in MDR-TB/HIV co-infected patients under ART and MDR-TB treatment, Mumbai, India.
Esdras Da Silva (316423), Helen S. Cox (80991), Bhanumati Varghese (316420), Petros Isaakidis (316418), Homa Mansoor (316421), Joanna Ladomirska (316422), Peter Saranchuk (272818), Emanuele Pontali (338435), Camilla Rodrigues (287811), Giovanni B. Migliori (139497), Giovanni Sotgiu (16787), Chiara Montaldo (338434), Tony Reid (56960)   +12 more
core   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Frequency of MDR and XDR Strains and Antibiotic Resistance Pattern of Acinetobacter baumannii Clinical Isolates in Sari Hospitals, Iran

Journal of Mazandaran University of Medical Sciences, 2020
Background and purpose: The prevalence of antibiotic resistance in Acinetobacter baumannii is increasing worldwide, causing significant clinical problems. This study aimed to determine the antibiotic resistance pattern of clinical A.
Maryam Asadi Jouybari, Hamid Reza Goli
doaj  

Investigation of the role of LRP in multidrug resistance [PDF]

, 1998
There have been many reports linking the overexpression of the lung resistance-related protein (LRP) with cross-resistance to chemotherapeutic drugs.
Byrne, Daragh
core  

Development and Validation of Urodynamic Report Writer: A Chat GPT App

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective Accurate interpretation and reporting of urodynamic studies are essential for diagnosis and management of lower urinary tract dysfunction, yet remain time‐consuming and operator‐dependent. To develop and validate the Urodynamic Report Writer App (URapp), a GPT‐4o‐based virtual assistant that supports interpretation of clinician ...
Riccardo Lombardo, Carolina Cerullo, Marta Santioni, Emanuele Pillitteri, Claudia Lorenti, Sabrina De Cillis, Cristian Fiori, Giorgia Tema, Antonio Franco, Beatrice Turchi, Matteo Romagnoli, Antonio Nacchia, Antonio Cicione, Antonio Pastore, Andrea Fuschi, Andrea Tubaro, Cosimo De Nunzio   +16 more
wiley   +1 more source