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Inhibitors of Multidrug Resistance (MDR) Have Affinity for MDR Substrates
Bioorganic and Medicinal Chemistry Letters, 2004 Multidrug-resistance (MDR) occurs in many bacterial species and tumour cells. MDR functions by membrane proteins which export drugs from cells, resulting in a low ineffective concentration of the drug. We have shown by molecular modelling that inhibitors of MDR have affinity for substrates of MDR transporters.
Glenn W Kaatz, Mire Zloh, Simon Gibbons
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Indian Journal of Tuberculosis, 2022
Tuberculosis is very common in young population, but it has emerged in a significant number in geriatric/elderly population (>60 Yrs. of age) as the population is ageing. Most cases of TB in the elderly are linked to the reactivation of lesions that have remained dormant.
Avdhesh Bansal, Shweta Arora
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Tuberculosis is very common in young population, but it has emerged in a significant number in geriatric/elderly population (>60 Yrs. of age) as the population is ageing. Most cases of TB in the elderly are linked to the reactivation of lesions that have remained dormant.
Avdhesh Bansal, Shweta Arora
openaire +2 more sources