Results 71 to 80 of about 63,034 (284)

A Matrix-Theoretic Approach to the Construction of Reversible DNA Codes Over F₄²t

IEEE Access
Let $n,k$ , and t be the positive integers. The primary aim of this paper is to introduce a new approach for the construction of reversible and reversible DNA codes using the concept of double-reflected matrices of any matrices over a commutative ring ...
Elif Segah Oztas, Amal S. Alali, Shakir Ali, Mohd Azeem, Muhammad S. M. Asri, Kok Bin Wong   +5 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

MDS array codes with independent parity symbols [PDF]

, 1995
A new family of maximum distance separable (MDS) array codes is presented. The code arrays contain p information columns and r independent parity columns, each column consisting of p-1 bits, where p is a prime.
Blaum, Mario, Bruck, Jehoshua, Vardy, Alexander   +2 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

MDS and MHDR Cyclic Codes over Finite Chain Rings

Journal of Mathematics
This work establishes a unique set of generators for a cyclic code over a finite chain ring. Towards this, we first determine the minimal spanning set and rank of the code.
Monika Dalal, Sucheta Dutt, Ranjeet Sehmi   +2 more
doaj   +1 more source

Some Connections Between Classical Coding and Network Coding Over Erroneous Cyclic Networks

IEEE Access, 2016
Recently, a framework was given for linear error-correcting network codes (LENCs) over cyclic networks on commutative rings. When the alphabet is considered as a rational power series ring, an LENC is referred to as a convolutional error-correcting ...
Vahid Samadi-Khaftari, Morteza Esmaeili, Thomas Aaron Gulliver   +2 more
doaj   +1 more source

New constructions of MDS codes with complementary duals

, 2017
Linear complementary-dual (LCD for short) codes are linear codes that intersect with their duals trivially. LCD codes have been used in certain communication systems. It is recently found that LCD codes can be applied in cryptography. This application of
Chen, Bocong, Liu, Hongwei
core   +1 more source

On negacyclic MDS-convolutional codes

Linear Algebra and its Applications, 2014
New families of classical and quantum optimal negacyclic convolutional codes are constructed in this paper. This optimality is in the sense that they attain the classical (quantum) generalized Singleton bound. The constructions presented in this paper are performed algebraically and not by computational search.
openaire   +2 more sources