Results 101 to 110 of about 37,729 (256)

Restoration of pharyngeal dilator muscle force in dystrophin-deficient (mdx) mice following co-treatment with neutralizing interleukin-6 receptor antibodies and urocortin-2 [PDF]

, 2017
New Findings: What is the central question of this study? We previously reported impaired upper airway dilator muscle function in the mdx mouse model of Duchenne muscular dystrophy (DMD).
Brannock, Molly, Burns, David P., Canavan, Leonie, Edge, Deirdre, Murphy, Kevin H., O'Halloran, Ken D., O'Malley, Dervla, Rowland, Jane   +7 more
core   +1 more source

Erythropoietin reduces the expression of myostatin in mdx dystrophic mice [PDF]

Brazilian Journal of Medical and Biological Research, 2014
Erythropoietin (EPO) has been well characterized as a renal glycoprotein hormone regulating red blood cell production by inhibiting apoptosis of erythrocyte progenitors in hematopoietic tissues. EPO exerts regulatory effects in cardiac and skeletal muscles. Duchenne muscular dystrophy is a lethal degenerative disorder of skeletal and cardiac muscle. In
Feder, David, Rugollini, M., Santomauro, A., Oliveira, Luciano P., Lioi, V. P., Santos, Rosangela Aparecida dos, Ferreira, Leonardo G., Nunes, Maria Tereza, Carvalho, Maria Helena, Delgado, Pilar O., Carvalho, Alzira A. S., Fonseca, Fernando Luiz Affonso UNIFESP   +11 more
openaire   +7 more sources

Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy

The Journal of Physiology, EarlyView.
Abstract figure legend This study investigated the effects of volitional exercise on muscle health in the more severe D2.mdx model of Duchenne muscular dystrophy (DMD). We showed that 8–10 weeks of a relatively high volume of voluntary wheel running (VWR) in D2.mdx animals augmented select muscle mass and normalized ex vivo muscle force compared to ...
Stephanie R. Mattina, Sean Y. Ng, Andrew I. Mikhail, Derek W. Stouth, Cora E. Jornacion, Irena A. Rebalka, Thomas J. Hawke, Vladimir Ljubicic   +7 more
wiley   +1 more source

Normalizing the Taylor expansion of non-deterministic {\lambda}-terms, via parallel reduction of resource vectors

, 2019
It has been known since Ehrhard and Regnier's seminal work on the Taylor expansion of $\lambda$-terms that this operation commutes with normalization: the expansion of a $\lambda$-term is always normalizable and its normal form is the expansion of the B\"
Vaux, Lionel
core   +2 more sources

Immunomodulatory amnion-derived mesenchymal stromal cells preserve muscle function in a mouse model of Duchenne muscular dystrophy

Stem Cell Research & Therapy, 2023
Background Duchenne muscular dystrophy (DMD) is an incurable genetic disease characterized by degeneration and necrosis of myofibers, chronic inflammation, and progressive muscle weakness resulting in premature mortality.
Yuko Nitahara-Kasahara, Soya Nakayama, Koichi Kimura, Sho Yamaguchi, Yuko Kakiuchi, Chikako Nito, Masahiro Hayashi, Tomoyuki Nakaishi, Yasuyoshi Ueda, Takashi Okada   +9 more
doaj   +1 more source

Filamented Light (FLight) Bioprinting of Mini‐Muscles with Self‐Renewal Potential

Advanced Materials, Volume 37, Issue 40, October 9, 2025.
This work presents the FLight biofabrication for engineering in vitro muscle constructs by photocrosslinking pristine collagen and fibrinogen using ruthenium. The resulting mini‐muscles retain in vivo‐like tissue organization and a Pax7⁺ cell pool.
Hao Liu, Michael Winkelbauer, Jakub Janiak, Patrick Weber, Ali Kerem Kalkan, Inseon Kim, Parth Chansoria, Ori Bar‐Nur, Marcy Zenobi‐Wong   +8 more
wiley   +1 more source

MIMO radar with broadband waveforms: Smearing filter banks and 2D virtual arrays [PDF]

, 2009
In this paper MIMO radars with broadband waveforms are considered. A time domain viewpoint is taken, which allows frequency invariant beamforming with a filter bank called the smearing filter bank.
Chen, Chun-Yang, Pal, Piya, Vaidyanathan, P. P.   +2 more
core   +2 more sources

Genomic prostate score and treatment selection in favourable intermediate‐risk prostate cancer

BJUI Compass
Objective To assess the factors associated with the use of active surveillance (AS) in NCCN favourable intermediate‐risk (FIR) prostate cancer (PCa) patients who received the 17‐gene Genomic Prostate Score (GPS) assay.
Eric Margolis, Benjamin H. Lowentritt, Christopher M. Pieczonka, John P. Bennett, Marina Pavlova, Joao Paulo Zambon, Jack Groskopf, Edward Uchio   +7 more
doaj   +1 more source

Transgenic overexpression of γ-cytoplasmic actin protects against eccentric contraction-induced force loss in mdx mice

Skeletal Muscle, 2011
Background γ-cytoplasmic (γ-cyto) actin levels are elevated in dystrophin-deficient mdx mouse skeletal muscle. The purpose of this study was to determine whether further elevation of γ-cyto actin levels improve or exacerbate the dystrophic phenotype of ...
Baltgalvis Kristen A, Jaeger Michele A, Fitzsimons Daniel P, Thayer Stanley A, Lowe Dawn A, Ervasti James M   +5 more
doaj   +1 more source

Exosomal CCT6A Secreted by Cancer‐Associated Fibroblasts Interacts with β‐Catenin to Enhance Chemoresistance and Tumorigenesis in Gastric Cancer

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Here, it is revealed that CAF‐secreted exosomal CCT6A enhances stemness, chemoresistance, and glycolysis in GC via the β‐catenin/c‐Myc/DDIT4‐TXNIP axis. Furthermore, CCT6P1, a pseudogene of CCT6A, is identified as upregulating CCT6A by competitively binding miR‐922, while c‐Myc transcriptionally activates both CCT6P1 and CCT6A.
Hui Sun, Tianqi Zhang, Xiaoyan Zhang, Yingxue Liu, Xu Wang, Xin Wang, Cong Tan, Shujuan Ni, Weiwei Weng, Meng Zhang, Lei Wang, Dan Huang, Xiaoyu Wang, Wenfeng Wang, Weiqi Sheng, Mi‐die Xu   +15 more
wiley   +1 more source