Results 111 to 120 of about 37,729 (256)

Temporal Bayesian classifiers for modelling muscular dystrophy expression data [PDF]

, 2006
The analysis of microarray data from time-series experiments requires specialised algorithms, which take the temporal ordering of the data into account. In this paper we explore a new architecture of Bayesian classifier that can be used to understand how
Hoen, PAC't, Liu, X, Tucker, A, Vinciotti, V   +3 more
core  

Validation of an hplc method for the determination of 1,7-dihydroxy-2,3-methylenedioxyxanthone in extracts obtained from Polygala cyparissias A. St. Hil. & Moq. (Polygalaceae) and evaluation of the influence of its content on the gastroprotective activity

Química Nova, 2014
Polygala cyparissias is a plant widespread in Southern Latin America. Recently, we demonstrated the gastroprotective activity of the extract, as well as for one of the isolated metabolites-1,7-dihydroxy-2,3-methylenedioxyxanthone (MDX).
Luiz Carlos Klein-Júnior, Sérgio Faloni de Andrade, Valdir Cechinel-Filho, Tania Mari Bellé Bresolin   +3 more
doaj   +1 more source

Altered nuclear dynamics in MDX myofibers

Journal of Applied Physiology, 2017
Duchenne muscular dystrophy (DMD) is a genetic disorder in which the absence of dystrophin leads to progressive muscle degeneration and weakness. Although the genetic basis is known, the pathophysiology of dystrophic skeletal muscle remains unclear.
Shama R. Iyer, Sameer B. Shah, Ana P. Valencia, Martin F. Schneider, Erick O. Hernández-Ochoa, Joseph P. Stains, Silvia S. Blemker, Richard M. Lovering   +7 more
openaire   +3 more sources

3D Topological Inorganic Electrides: Screening, Properties, and Applications

Advanced Science, Volume 12, Issue 37, October 6, 2025.
In inorganic electrides, zero‐, one‐, and two‐dimensional (0D, 1D, and 2D) interstitial anionic electrons interconnect within lattice cavities, collectively forming a three‐dimensional (3D) network, further coupling magnetism and topological features, leading to the emergence of 3D topological inorganic electrides.
Zhenzhou Guo, Weizhen Meng, Qianwen Zhang, Xia Cheng, Shiyao Wang, Yalong Jiao, Xiaoming Zhang, Ying Liu, Tie Yang   +8 more
wiley   +1 more source

Hybrid Passive Control Strategies for Reducing the Displacements at the Base of Seismic Isolated Structures [PDF]

, 2019
In this paper, the use of hybrid passive control strategies to mitigate the seismic response of a base-isolated structure is examined. The control performance of three different types of devices used for reducing base displacements of isolated buildings ...
Di Matteo A., Masnata C., Pirrotta A.
core   +1 more source

Sildenafil Ameliorates Cardiomyopathy in mdx Mice

The FASEB Journal, 2009
Duchenne muscular dystrophy (DMD) is the most prevalent type of muscular dystrophy and is the result of an X‐linked mutation in the dystrophin gene. The progression of skeletal muscle damage is rapid in DMD patients and cardiomyopathy soon follows. We have investigated whether or not sildenafil citrate, a phosphodiesterase 5 (PDE5) inhibitor, can be ...
Heidi Gray, Joseph A. Beavo, Justin M. Percival, Stanley C. Froehner, Candace M Parchen, Dao-Fu Dai   +5 more
openaire   +2 more sources

MyomiRs Expression in Limb Girdle Muscular Dystrophy

IUBMB Life, Volume 77, Issue 10, October 2025.
ABSTRACT This manuscript is a comprehensive review focused on the role of microRNAs (miRs)—short RNA molecules—in Limb Girdle Muscular Dystrophy (LGMD). LGMD encompasses various and heterogeneous rare genetic neuromuscular diseases, characterized by the progressive wasting and deterioration of muscle fibers, predominantly affecting the pelvic and ...
G. Breveglieri, M. T. Altieri, M. T. Rodia, R. Costa, F. Frabetti, G. Cenacchi, G. Sabbioni, M. Borgatti   +7 more
wiley   +1 more source

Inverse‐Perovskite Ba3BO (B = Si and Ge) as a High Performance Environmentally Benign Thermoelectric Material with Low Lattice Thermal Conductivity

Advanced Science
High energy‐conversion efficiency (ZT) of thermoelectric materials has been achieved in heavy metal chalcogenides, but the use of toxic Pb or Te is an obstacle for wide applications of thermoelectricity.
Xinyi He, Shigeru Kimura, Takayoshi Katase, Terumasa Tadano, Satoru Matsuishi, Makoto Minohara, Hidenori Hiramatsu, Hiroshi Kumigashira, Hideo Hosono, Toshio Kamiya   +9 more
doaj   +1 more source

Decrease in Prosaposin in the Dystrophic mdx Mouse Brain

PLoS ONE, 2013
Duchenne muscular dystrophy caused by a mutation in the X-linked dystrophin gene induces metabolic and structural disorders in the brain. A lack of dystrophin in brain structures is involved in impaired cognitive function. Prosaposin (PS), a neurotrophic factor, is abundant in the choroid plexus and various brain regions.
Hui Ling Gao, Hiroaki Nabeka, Naoto Kobayashi, Cheng Li, Seiji Matsuda, Tetsuya Shimokawa, Zhan You Wang, Ya Ming Cao, Shouichiro Saito   +8 more
openaire   +5 more sources

CSE/H2S/SESN2 Signalling Mediates the Protective Effect of Exercise Against Immobilization‐Induced Muscle Atrophy in Mice

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Hydrogen sulphide (H2S), a gasotransmitter synthesized by cystathionine‐γ‐lyase (CSE), exhibits antioxidant properties and may mimic exercise‐induced muscle protection. However, its mechanistic role in muscle atrophy and exercise intervention remains unclear.
Xiuru Li, Yating Huang, Xuege Yang, Sujuan Liu, Yanmei Niu, Li Fu   +5 more
wiley   +1 more source