Targeting mitochondrial quality control: Ginsenoside Rg1 as a therapeutic candidate for neuromuscular diseases. [PDF]
Cai X +6 more
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Dystrophin Restorative and Compensatory Gene Addition Therapies for Duchenne Muscular Dystrophy: Could CRISPRa Provide a Realistic Alternative? [PDF]
Rostamitehrani Z, Javed R, Popplewell L.
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Codon-optimized human Smad7 gene therapy enhances skeletal muscle mass and function in a murine model of Duchenne muscular dystrophy. [PDF]
Rodgers BD, Ward CW.
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Tauroursodeoxycholic acid-induced increase in ectopic muscle mineralization occurs exclusively in dystrophic muscles and is independent of endoplasmic reticulum stress. [PDF]
Róg J +11 more
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Mineralocorticoid receptor antagonists reduce inflammatory signaling independent of myofiber mineralocorticoid receptor. [PDF]
Lowe J +5 more
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Evaluation of a novel PCR-based assay for the detection of <i>Candida auris</i> colonization. [PDF]
Leonard J +6 more
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THE 2022MY Acura MDX takes its place as the brand's new flagship model, with an all-new platform and double-wishbone front suspension. We spoke exclusively to the MDX's dynamics team for the details
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Cerebral water accumulation-clinically denoted as brain edema-is a potentially life threatening complication of almost every intracranial neuropathological state. The molecular membrane water channel aquaporin-4 (AQP4) has been shown to be present at the blood-brain barrier (BBB) where it plays pivotal role in the transport of water between the tissue ...
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Mdx muscle grafts retain the mdx phenotype in normal hosts
Muscle & Nerve, 1989AbstractWhole muscle grafts were made between mdx and normal mice to investigate whether the mdx myopathic lesion is intrinsic to mdx muscle or is a property of its environment. Grafts were examined between 20 and 101 days. Unequivocal necrotic muscle fibers and/or newly formed basophilic myotubes were noted in 8 of 16 grafts of mdx muscle made in ...
J E, Morgan +2 more
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Neurocognitive Impairment in mdx Mice
Molecular Neurobiology, 2019Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that affects muscles and also the brain, resulting in memory and behavioral problems. In the pathogenesis of DMD, inflammation is an important factor during the degenerative process. However, the involvement of the brain is still unclear. Therefore, the objective of this study is to evaluate
Clarissa M. Comim +11 more
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