Results 181 to 190 of about 34,705 (216)
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Posttetanic potentiation in mdx muscle

Journal of Muscle Research and Cell Motility, 2010
X-linked muscular dystrophy of the mouse (mdx) has been reported to progressively remodel skeletal muscle to preferentially reduce fast fiber composition. Despite this, mdx muscle displays normal levels of posttetanic potentiation (PTP). Since PTP may primarily depend on phosphorylation of the myosin regulatory light chain (RLC) in fast muscle fibers ...
Ian Curtis, Smith   +4 more
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Genetically dystrophic mdx/mdx mice exhibit decreased response to nicotine in passive avoidance

Neuroreport, 2002
mdx mice are considered as a genetic homologous of human Duchenne muscular dystrophy. Recent evidence demonstrates that in mouse sympathetic ganglion dystrophin is involved in the stabilization of nicotinic acetylcholine receptor clusters. The purpose of this study was to verify possible effects of dystrophin alterations at the central level.
Roberto Coccurello   +4 more
openaire   +4 more sources

Introduction to MDX

2011
In this chapter, you’ll work with Multidimensional Expressions (MDX), which is the native query language for SQL Server Analysis Services (SSAS). MDX is a SQL-like language used to query SSAS cubes.
Guy Fouché, Lynn Langit
openaire   +1 more source

Recursion in MDX

2002
The term ‘recursion’ is used to describe something that references itself. My favorite definition of recursion is found in the joke.
Mark Whitehorn   +2 more
openaire   +1 more source

Dystrophin distribution in heterozygote mdx mice

Muscle & Nerve, 1989
AbstractThe distribution of dystrophin in myofibers from normal, mdx hemizygous, and mdx heterozygous mice was studied at various times in development. While normal mice exhibit dystrophin immunostaining around the entire fiber periphery regardless of age, mdx hemizygous mice exhibit no staining (0–35 days). In contrast, young (10 day) heterozygous mdx
S C, Watkins   +3 more
openaire   +2 more sources

Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice

American Journal of Physiology-Cell Physiology, 1997
Diaphragm muscles of young (4- to 6-mo-old) mdx mice show severe fiber necrosis and have normalized forces and powers 60 and 46% of the values for control C57BL/10 mice. In contrast, microinjection of mdx mouse embryos with a truncated dystrophin minigene has produced young transgenic mdx (tg-mdx) mice with a level of dystrophin expression and ...
G S, Lynch   +5 more
openaire   +2 more sources

MDX-060. Medarex.

Current opinion in investigational drugs (London, England : 2000), 2006
Medarex is developing the antibody MDX-060 for the potential treatment of CD30+ lymphomas, such as Hodgkin's disease and anaplastic large cell lymphomas. Phase I/II clinical trials were underway by December 2002.
Xiu Feng, Hu, Pei Xiang, Xing
openaire   +1 more source

Neuromuscular transmission in the mdx mouse

Muscle & Nerve, 1990
AbstractThe mdx mouse is an animal model for human Duchenne dystrophy. In both disorders, the muscle fiber plasma membrane is rendered selectively vulnerable by dystrophin deficiency. In both disorders there are also ultrastructural abnormalities involving the postsynaptic membrane of the neuromuscular junction.
A, Nagel, F, Lehmann-Horn, A G, Engel
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Dystrophin in control and mdx retina

Brain and Development, 1991
To determine whether or not dystrophin really exists in the outer plexiform layer (OPL) of the retina, we studied control and mdx mice, using four kinds of polyclonal antibodies (DMDP-II, 60 kd, 30 kd and DMDP-IV) against dystrophin. Although control OPL showed a positive immunohistochemical reaction with all four antibodies, mdx OPL showed a positive ...
J, Zhao   +4 more
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Muscle development in mdx mutant mice

Muscle & Nerve, 1984
AbstractMechanical and contractile properties of tibialis anterior (TA) muscles from X‐linked muscular dystrophic (mdx) mutant mice at different stages of development are compared to those of muscles from normal control animals. There is no difference between the tension output, speeds of contraction and relaxation, and weight of TA muscles from mutant
J, Dangain, G, Vrbova
openaire   +2 more sources

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