Results 241 to 250 of about 37,729 (256)
Some of the next articles are maybe not open access.
Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice
American Journal of Physiology-Cell Physiology, 1997Diaphragm muscles of young (4- to 6-mo-old) mdx mice show severe fiber necrosis and have normalized forces and powers 60 and 46% of the values for control C57BL/10 mice. In contrast, microinjection of mdx mouse embryos with a truncated dystrophin minigene has produced young transgenic mdx (tg-mdx) mice with a level of dystrophin expression and ...
John A. Faulkner +5 more
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Phenotype of dystrophinopathy in old MDX mice
The Anatomical Record, 1995AbstractBackground: Mdx mutant mice, like patients with Duchenne Muscular Dystrophy (DMD), lack dystrophin, a subsarcolemmal protein, that results in myofiber necrosis. However young mdx mice, in contrast to DMD children, exhibit a successful muscle regeneration and not an extensive fibrosis.Methods: Old mdx mice were monitored clinically up to their ...
Alain Sebille +2 more
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2002
The first edition of this book (18 chapters long) was written as an easy introduction to MDX. Assuming we succeeded in this task, by now you should be over that initial steep learning curve. So, when we came to add this extra material for the second edition we felt that it was appropriate to change gear a little and look at some more advanced topics ...
Mark Whitehorn +2 more
openaire +2 more sources
The first edition of this book (18 chapters long) was written as an easy introduction to MDX. Assuming we succeeded in this task, by now you should be over that initial steep learning curve. So, when we came to add this extra material for the second edition we felt that it was appropriate to change gear a little and look at some more advanced topics ...
Mark Whitehorn +2 more
openaire +2 more sources
Bulletin of Experimental Biology and Medicine, 2013
In mdx mice, mutation in the muscle protein dystrophin gene results in the development of chronic degeneration of the muscle tissue. We performed a comparative analysis of blood cytokine levels in mdx mice, classical black mice and mice with additional genetic defect responsible for the manifestations of oculocutaneous albinism. In mdx albino mice, the
M. A. Stenina +3 more
openaire +3 more sources
In mdx mice, mutation in the muscle protein dystrophin gene results in the development of chronic degeneration of the muscle tissue. We performed a comparative analysis of blood cytokine levels in mdx mice, classical black mice and mice with additional genetic defect responsible for the manifestations of oculocutaneous albinism. In mdx albino mice, the
M. A. Stenina +3 more
openaire +3 more sources
2012
Multidimensional Expressions (MDX) is a Microsoft-owned specification, not an open standard language. But, it has been adopted by many vendors and is considered an industry standard for querying and manipulating multidimensional data for SSAS.
Randal Root, Caryn Mason
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Multidimensional Expressions (MDX) is a Microsoft-owned specification, not an open standard language. But, it has been adopted by many vendors and is considered an industry standard for querying and manipulating multidimensional data for SSAS.
Randal Root, Caryn Mason
openaire +2 more sources
Dystrophin gene transcripts skipping the mdx mutation
Muscle & Nerve, 1997The mdx mouse, an animal model used to study Duchenne muscular dystrophy, has a nonsense mutation in exon 23 of the dystrophin gene which should result in a truncated protein that cannot be correctly localized at the sarcolemma of the muscle fibers.
Wilton, S.D., Dye, D.E., Laing, N.G.
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P.1.18 NMR imaging comparison of dystrophic mouse models: mdx, Large, mdx/Large
Neuromuscular Disorders, 2013The mdx is the mouse model for Duchenne muscular dystrophy (MD), but with a benign phenotype. The large-myd mouse (Lg) has a mutation in the glycosyltransferase like Large gene and models the Congenital MD 1D, with a severe phenotype. The double mutant mdx/Lg, developed in our lab (1), has a more severe phenotype than both parental lineages. Dystrophic
B. Matot +8 more
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Postnatal changes in sarcolemmal organization in the mdx mouse
Neuromuscular Disorders, 2005The tibialis anterior muscles of mdx mice degenerate between 3 and 4 weeks after birth and then partially recover. We show that the membrane cytoskeleton at the mdx sarcolemma is disorganized at 18-days postnatal, and becomes more disorganized at 4 weeks compared to earlier or later times.
Patrick Reed, Robert J. Bloch
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Therapeutic screening in the mdx mouse
Neuromuscular Disorders, 2000CONTE, Diana, DE LUCA, Annamaria
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Nature, 1991