Results 41 to 50 of about 38,496 (259)
Investigating synthetic oligonucleotide targeting of miR31 in Duchenne muscular dystrophy [PDF]
, 2016 Exon-skipping via synthetic antisense oligonucleotides represents one of the most promising potential therapies for Duchenne muscular dystrophy (DMD), yet this approach is highly sequence-specific and thus each oligonucleotide is of benefit to only a ...
Hildyard, J C W, Wells, D J
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Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice. [PDF]
PLoS ONE, 2013 Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans and in mdx mice by a severe and progressive destruction of muscle fibers, inflammation ...
Francisco Altamirano +6 more
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Revertant fibres and dystrophin traces in Duchenne muscular dystrophy: Implication for clinical trials [PDF]
, 2010 Duchenne muscular dystrophy (DMD) is characterised by the absence of dystrophin in muscle biopsies, although residual dystrophin can be present, either as dystrophin-positive (revertant) fibres or traces.
Arechavala-Gomeza, V +12 more
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Langerhans Cell Histiocytosis Presenting as Uncontrolled Asthma
Case Reports in Medicine, 2013 Langerhans cell histiocytosis (LCH) is an uncommon disorder affecting primarily young adult smokers. It is characterized by abnormal proliferation of Langerhans cells, specialized monocyte-macrophage lineage antigen-presenting cells.
Frederic A. Rawlins +3 more
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Data in Brief, 2018 Here we present original data related to the research paper entitled “Proteome analysis in dystrophic mdx mouse muscle reveals a drastic alteration of Key Metabolic and Contractile Proteins after chronic exercise and the potential modulation by anti ...
Tania Gamberi +8 more
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Frontiers in Physiology, 2022 Duchenne muscular dystrophy (DMD) is an X-linked recessive fatal muscular disease. Gene therapy, cell therapy, and drug therapy are currently the most widely used treatments for DMD.
Yuhui Su, Yuhui Su, Yafeng Song
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An Internal Observability Estimate for Stochastic Hyperbolic Equations [PDF]
, 2016 This paper is addressed to establishing an internal observability estimate for some linear stochastic hyperbolic equations. The key is to establish a new global Carleman estimate for forward stochastic hyperbolic equations in the $L^2$-space.
Fu, Xiaoyu, Liu, Xu, Lu, Qi, Zhang, Xu
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¹³C NMR metabolomics: applications at natural abundance. [PDF]
, 2014 (13)C NMR has many advantages for a metabolomics study, including a large spectral dispersion, narrow singlets at natural abundance, and a direct measure of the backbone structures of metabolites.
Clendinen, Chaevien +7 more
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EcoEnergyDeveloping high‐efficiency and environmentally‐friendly thermoelectric materials has been a significant challenge. Conventional thermometric materials consist of heavy (toxic) elements to reduce thermal conductivity (κ), while we demonstrated light ...
Masatoshi Kimura +6 more
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Indicators of increased ER stress and UPR in aged D2-mdx and human dystrophic skeletal muscles
Frontiers in Physiology, 2023 Duchenne muscular dystrophy (DMD) is a progressive muscle disease that results in muscle wasting, wheelchair dependence, and eventual death due to cardiac and respiratory complications.
Swathy Krishna +5 more
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