Results 71 to 80 of about 37,928 (204)
Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific
The FEBS Journal, EarlyView.Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty +2 more
wiley +1 more source
Journal of Prosthodontics, EarlyView.Abstract Purpose To explore the impact of zirconia types, coloring methods, and surface finishing on the color stability of monolithic multilayered polychromatic zirconia after artificial aging, including thermocycling and simulated toothbrushing. Materials and Methods Eighty square‐shaped zirconia samples were divided into 2 types (M3Y‐TZP and M6Y‐PSZ)
Feras M. Abounassif +5 more
wiley +1 more source
Clinical application of additive manufacturing in maxillofacial prosthetics: A scoping review
Journal of Prosthodontics, EarlyView.Abstract Purpose Digital workflows provide significant advances in prosthodontics, especially in terms of accuracy, reduced treatment duration, and quality of life. Moreover, additive manufacturing (AM) is particularly adapted for the fabrication of personalized complex prototypes required for the prosthetic rehabilitation of maxillofacial defects ...
Hélène Magro +2 more
wiley +1 more source
Frontiers in Cell and Developmental Biology, 2019 Differentiated mammalian cells and tissues, such as skeletal muscle fibers, acquire an organization of Golgi complex and microtubules profoundly different from that in proliferating cells and still poorly understood.
Sarah Oddoux +5 more
doaj +1 more source
, 2019 It has been known since Ehrhard and Regnier's seminal work on the Taylor expansion of $\lambda$-terms that this operation commutes with normalization: the expansion of a $\lambda$-term is always normalizable and its normal form is the expansion of the B\"
Vaux, Lionel
core +2 more sources
MIMO radar with broadband waveforms: Smearing filter banks and 2D virtual arrays [PDF]
, 2009 In this paper MIMO radars with broadband waveforms are considered. A time domain viewpoint is taken, which allows frequency invariant beamforming with a filter bank called the smearing filter bank.
Chen, Chun-Yang +2 more
core +2 more sources
Zika virus surveillance post‐epidemic in blood donors from São Paulo, Brazil 2016–2020
Transfusion Medicine, EarlyView.Abstract Introduction Zika virus (ZIKV) is primarily transmitted through the bite of the Aedes aegypti mosquito, though transmission via blood transfusion has also been documented. During the 2015 ZIKV epidemic in Brazil, severe complications were observed in pregnant women, leading to fetal microcephaly. This study evaluated the persistence of ZIKV in
Suzete Cleusa Ferreira +12 more
wiley +1 more source
Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy. [PDF]
PLoS ONE, 2018 Cardiac failure is a major cause of mortality in patients with Duchenne muscular dystrophy (DMD). Antisense-mediated exon skipping has the ability to correct out-of-frame mutations in DMD to produce truncated but functional dystrophin.
Alison M Blain +11 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend This study investigated the effects of volitional exercise on muscle health in the more severe D2.mdx model of Duchenne muscular dystrophy (DMD). We showed that 8–10 weeks of a relatively high volume of voluntary wheel running (VWR) in D2.mdx animals augmented select muscle mass and normalized ex vivo muscle force compared to ...
Stephanie R. Mattina +7 more
wiley +1 more source