Results 71 to 80 of about 34,705 (216)

Normalizing the Taylor expansion of non-deterministic {\lambda}-terms, via parallel reduction of resource vectors

, 2019
It has been known since Ehrhard and Regnier's seminal work on the Taylor expansion of $\lambda$-terms that this operation commutes with normalization: the expansion of a $\lambda$-term is always normalizable and its normal form is the expansion of the B\"
Vaux, Lionel
core   +3 more sources

On an Aggregation Theory for Indicators Expressing Behaviors of Complex Systems With an Application to Sustainability

Sustainable Development, EarlyView.
ABSTRACT Certain attributes of large‐scale complex systems are often expressed through sets of indicators. For example, the sustainability of an entity, be it a nation, a city, an energy system, a corporation etc., can be effectively represented by indicators and corresponding data series.
Vassilis S. Kouikoglou, Yannis A. Phillis   +1 more
wiley   +1 more source

Importância do camundongo mdx na fisiopatologia da distrofia muscular de Duchenne The importance of mdx mouse in the pathophysiology of Duchenne's muscular distrophy

Arquivos de Neuro-Psiquiatria, 1997
O camundongo mdx desenvolve distrofia muscular recessiva ligada ao cromossoma X (locus Xp21.1) e não expressa distrofina. Embora não apresente intensa fibrose do tecido muscular e acúmulo de tecido adiposo, é considerado o modelo animal mais adequado da ...
Sandra Lopes Seixas, Jussara Lagrota-Cândido, Wilson Savino, Thereza Quirico-Santos   +3 more
doaj   +1 more source

An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells. [PDF]

, 2013
Duchenne muscular dystrophy is a progressive and incurable neuromuscular disease caused by genetic and biochemical defects of the dystrophin-glycoprotein complex.
Borges, Luciene, Chamberlain, Jeffrey S, Darabi, Radbod, Ervasti, James M, Filareto, Antonio, Iacovino, Michelina, Kyba, Michael, Mayerhofer, Timothy, McIvor, R Scott, Parker, Sarah, Perlingeiro, Rita CR, Schaaf, Tory   +11 more
core   +2 more sources

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup, Joachim Boers, Line Winther Gustafson, Berit Andersen, Lone Kjeld Petersen, Pinar Bor, Joost Gribnau, Wim G. V. Quint, Henk Van Den Munckhof, Mette Tranberg, Anne Hammer   +10 more
wiley   +1 more source

Misplaced Golgi Elements Produce Randomly Oriented Microtubules and Aberrant Cortical Arrays of Microtubules in Dystrophic Skeletal Muscle Fibers

Frontiers in Cell and Developmental Biology, 2019
Differentiated mammalian cells and tissues, such as skeletal muscle fibers, acquire an organization of Golgi complex and microtubules profoundly different from that in proliferating cells and still poorly understood.
Sarah Oddoux, Davide Randazzo, Aster Kenea, Bruno Alonso, Kristien J. M. Zaal, Evelyn Ralston   +5 more
doaj   +1 more source

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy. [PDF]

PLoS ONE, 2018
Cardiac failure is a major cause of mortality in patients with Duchenne muscular dystrophy (DMD). Antisense-mediated exon skipping has the ability to correct out-of-frame mutations in DMD to produce truncated but functional dystrophin.
Alison M Blain, Elizabeth Greally, Graham McClorey, Raquel Manzano, Corinne A Betts, Caroline Godfrey, Liz O'Donovan, Thibault Coursindel, Mike J Gait, Matthew J Wood, Guy A MacGowan, Volker W Straub   +11 more
doaj   +1 more source

Restoration of pharyngeal dilator muscle force in dystrophin-deficient (mdx) mice following co-treatment with neutralizing interleukin-6 receptor antibodies and urocortin-2 [PDF]

, 2017
New Findings: What is the central question of this study? We previously reported impaired upper airway dilator muscle function in the mdx mouse model of Duchenne muscular dystrophy (DMD).
Brannock, Molly, Burns, David P., Canavan, Leonie, Edge, Deirdre, Murphy, Kevin H., O'Halloran, Ken D., O'Malley, Dervla, Rowland, Jane   +7 more
core   +1 more source

Transcolonic Endoscopic Appendectomy: A Single‐Step “Two‐In‐One” Approach for Recurrent Appendicitis With Appendiceal Orifice Lesions

Journal of Digestive Diseases, EarlyView.
Transcolonic endoscopic appendectomy (TEA) is a minimally invasive, single‐step “two‐in‐one” procedure for recurrent appendicitis with appendiceal orifice lesions. It enables precise resection of both appendix and associated lesions, with a novel closure method reducing operative time and improving safety.
Hao Wu, Zhu Kai Chen, Ai Ping Xu, Yuan Chu, Li Zhang, Jing Jing Lian, Tao Chen, Mei Dong Xu   +7 more
wiley   +1 more source

Design and fabrication of a low cost implantable bladder pressure monitor [PDF]

, 2009
In the frame of the Flemish Community funded project Bioflex we developed and fabricated an implant for short term (< 7 days) bladder pressure monitoring, and diagnosis of incontinence.
Axisa, Fabrice, Cornelissen, Maria, De Smet, N, Jourand, P, Lippens, Evi, Puers, R, Rymarczyk-Machal, Monika, Schacht, Etienne, Vanfleteren, Jan   +8 more
core   +2 more sources