Results 141 to 150 of about 1,104,554 (244)

Failure to resolve inflammation contributes to juvenile onset cardiac damage in a mouse model of Duchenne muscular dystrophy

Cell Death and Disease
Absence of dystrophin protein causes cardiac dysfunction in patients with Duchenne muscular dystrophy (DMD). Unlike boys with DMD, the common mouse model of DMD (B10-mdx) does not manifest cardiac deficits until late adulthood.
James S. Novak, Amy Lischin, Prech Uapinyoying, Ravi Hindupur, Young Jae Moon, Surajit Bhattacharya, Sarah Tiufekchiev-Grieco, Victoria Barone, Davi A. G. Mázala, Iteoluwakishi H. Gamu, Gabriela Walters, Jyoti K. Jaiswal   +11 more
doaj   +1 more source

Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice [PDF]

, 2017
Aims Duchenne muscular dystrophy (DMD) is a severe striated muscle disease due to the absence of dystrophin. Dystrophin deficiency results in dysfunctional sodium channels and conduction abnormalities in hearts of mdx mice. Disease progression in the mdx
Abriel, Hugues, Albesa, Maxime, Ogrodnik, Jakob, Rougier, Jean-Sébastien   +3 more
core  

Multiomics Analysis of the mdx/mTR Mouse Model of Duchenne Muscular Dystrophy [PDF]

, 2019
Douglas W. Van Pelt, Yalda A. Kharaz, Dylan C. Sarver, Logan R. Eckhardt, Justin T. Dzierzawski, Nathaniel P. Disser, Alex N. Piacentini, Eithne Comerford, Brian McDonagh, Christopher L. Mendias   +9 more
openalex   +1 more source

Expression and function of four AAV-based constructs for dystrophin restoration in the mdx mouse model of Duchenne muscular dystrophy. [PDF]

Biol Open, 2023
Potter RA, Griffin DA, Heller KN, Mendell JR, Rodino-Klapac LR.   +4 more
europepmc   +1 more source

Dystrophin Cytochemistry in Mdx Mouse Muscles Injected with Labeled Normal Myoblasts

Cell Transplantation, 1992
A new technique enables correlation of dystrophin expression with the location of donor versus host nuclei in the same sections of mdx mouse muscle injected with normal myoblasts. Myoblasts from C57BL/6J mice or from humans were labeled with 0.01% fluoro-
Ming Chen, Hua-Ju Li, Qiuwen Fang, Tena G. Goodwin, J. Ann Florendo, Peter K. Law   +5 more
doaj   +1 more source

Humanization of the mdx Mouse Phenotype for Duchenne Muscular Dystrophy Modeling: A Metabolic Perspective. [PDF]

J Neuromuscul Dis, 2023
Donen G, Milad N, Bernatchez P.
europepmc   +1 more source

Dietary Phosphorus Overload Aggravates the Phenotype of the Dystrophin-Deficient mdx Mouse [PDF]

, 2014
E. Wada, Mizuko Yoshida, Yoriko Kojima, Ikuya Nonaka, Kazuya Ohashi, Yosuke Nagata, Masataka Shiozuka, Munehiro Date, Tetsuo Higashi, Ichizo Nishino, Ryoichi Matsuda   +10 more
openalex   +1 more source

Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin receptor agonist ALY688. [PDF]

Exp Physiol, 2023
Bellissimo CA, Castellani LN, Finch MS, Murugathasan M, Gandhi S, Sweeney G, Abdul-Sater AA, MacPherson REK, Perry CGR.   +8 more
europepmc   +1 more source

Oligonucleotide Enhancing Compound Increases Tricyclo-DNA Mediated Exon-Skipping Efficacy in the Mdx Mouse Model. [PDF]

Cells, 2023
Bizot F, Fayssoil A, Gastaldi C, Irawan T, Phongsavanh X, Mansart A, Tensorer T, Brisebard E, Garcia L, Juliano RL, Goyenvalle A.   +10 more
europepmc   +1 more source

Issue Information

Experimental Physiology, Volume 110, Issue 12, Page 2057-2062, December 1, 2025.
wiley   +1 more source