Results 171 to 180 of about 18,188 (219)

The panniculus carnosus muscle: A novel model of striated muscle regeneration that exhibits sex differences in the mdx mouse. [PDF]

Sci Rep, 2019
Bahri OA, Naldaiz-Gastesi N, Kennedy DC, Wheatley AM, Izeta A, McCullagh KJA.   +5 more
europepmc   +1 more source

Humanizing the mdx mouse model of DMD: the long and the short of it. [PDF]

NPJ Regen Med, 2018
Yucel N, Chang AC, Day JW, Rosenthal N, Blau HM.   +4 more
europepmc   +1 more source

A Borophosphate Glass Doped with Cobalt Oxide Improves Skeletal Muscle Structure and Function in Myopathic Mice. [PDF]

J Funct Biomater
Kendra JA, Naman AG, Blatt RL, Zingariello CD, Brow RK, Segal SS, Morton AB.   +6 more
europepmc   +1 more source

Osmolytes and their therapeutic applicability in the mdx mouse

, 2023
openaire   +1 more source

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Somatic reversion/suppression of the mouse mdx phenotype in vivo

Journal of the Neurological Sciences, 1990
The mdx mouse has a myopathy caused by dystrophin deficiency, and is therefore biochemically and genetically homologous to human Duchenne muscular dystrophy. While mdx mouse muscle shows no dystrophin by immunoblotting, a very small percentage of myofibers appear clearly dystrophin-positive by immunofluorescence microscopy.
E P, Hoffman, J E, Morgan, S C, Watkins, T A, Partridge   +3 more
openaire   +4 more sources

Evolution of the mdx mouse cardiomyopathy: physiological and morphological findings

Neuromuscular Disorders, 2004
Heart failure is a major cause of death in boys with Duchenne muscular dystrophy. In order to determine if the cardiac function of the mdx mouse is similarly disturbed, we performed murine echocardiograms and left heart catheterization studies, along with morphometric analysis of cardiac fibrosis.
John G, Quinlan, Harvey S, Hahn, Brenda L, Wong, John N, Lorenz, Alexandra S, Wenisch, Linda S, Levin   +5 more
openaire   +4 more sources

Neuromuscular transmission in the mdx mouse

Muscle & Nerve, 1990
AbstractThe mdx mouse is an animal model for human Duchenne dystrophy. In both disorders, the muscle fiber plasma membrane is rendered selectively vulnerable by dystrophin deficiency. In both disorders there are also ultrastructural abnormalities involving the postsynaptic membrane of the neuromuscular junction.
A, Nagel, F, Lehmann-Horn, A G, Engel
openaire   +2 more sources

Muscular weakness in the mdx mouse

Journal of the Neurological Sciences, 1993
mdx mice are believed to be virtually free from neuromuscular symptoms, despite the presence of a degenerative/regenerative process that involves all skeletal muscles. We analyzed both the spontaneous motility and treadmill motor activity of mdx mice aged 15 days to 6 months.
Muntoni F., Mateddu A., Marchei F., Clerk A., SERRA, Gino   +4 more
openaire   +3 more sources

Axonal transport in mdx mouse sciatic nerve

Journal of the Neurological Sciences, 1989
Anterograde and retrograde flows of acetylcholinesterase (AChE) in sciatic nerves of adult mdx mice were compared with those of normal mice. Specific molecular forms of AChE were resolved by high-performance liquid chromatography such that slow anterograde (G1 + G2), fast anterograde and fast retrograde (G4 and A12) flows could be simultaneously ...
S, Yamashita, H, Takenaka, S, Sugimoto, E, Chihara, A, Sawada, S, Matsukura, M, Hamada   +6 more
openaire   +2 more sources

Twitch and tetanus in mdx mouse muscle

Muscle & Nerve, 1992
AbstractWe compared mdx and C57BL10 anterior tibial muscle force in situ (single pulse, multiple pulse, staircase, posttetanic potentiation, and fatiguing stimulation patterns) to define muscle strength, physiology, and fatigue resistance. The relatively hypertrophied mdx muscle showed: reduced strength (N/cm2), an increased twitch‐tetanus ratio, and ...
J G, Quinlan, S R, Johnson, M K, McKee, S P, Lyden   +3 more
openaire   +2 more sources