Results 61 to 70 of about 449,466 (261)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Using linear programming method to estimate parameters of linear regression model by absolute deviation [PDF]
المجلة العراقية للعلوم الاحصائية, 2011 This work deals with descriptive summary of linear programming subject, and describes least square method for estimating regression parameters. As well as using other methods in order to estimate the parameters unconventional on reduced variance (or ...
doaj +1 more source
Multiperiod Mean Absolute Deviation Uncertain Portfolio Selection
Industrial Engineering and Management Systems, 2016 Multiperiod portfolio selection problem attracts more and more attentions because it is in accordance with the practical investment decision-making problem. However, the existing literature on this field is almost undertaken by regarding security returns as random variables in the framework of probability theory.
openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Application of Trend Detection Methods in Monitoring Physiological Signals [PDF]
Journal of Systemics, Cybernetics and Informatics, 2004 This paper presents a comparative study of various trend detection methods developed using fuzzy logic, statistical, and regression techniques. A new method that uses noise rejection fuzzy clustering is also proposed in the paper to enhance the ...
William W. Melek +3 more
doaj
How to choose and interpret similarity indices to quantify the variability in gait joint kinematics
International Biomechanics, 2018 Repeatability and reproducibility indices are often used in gait analysis to validate models and assess patients in their follow-up. When comparing joint kinematics, their interpretation can be ambiguous due to a lack of understanding of the exact ...
Roberto Di Marco +5 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Fractal Geometry: Surface Characterization of Printing Paper
Fractal and FractionalThis study investigates the surface characteristics of printing papers using fractal geometry, focusing on surface roughness and surface friction as independent properties.
Yong Ju Lee +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source