Results 61 to 70 of about 2,392,377 (346)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Multi-Objective Transport System Based on Regression Analysis and Genetic Algorithm Using Transport Data

open access: yesIEEE Access, 2019
Intelligent transportation system (ITS) is a cutting-edge traffic solution employing state-of-the-art information and communication technologies. Optimized bus-scheduling, being an integral part of ITS, ensures safety, efficiency, traffic congestion ...
Moubeen Farooq Khan   +3 more
doaj   +1 more source

Peramalan Permintaan Produk Roti pada Industri “Tiara Rizki” di Kelurahan Boyaoge Kecamatan Tatanga Kota Palu [PDF]

open access: yes, 2016
This study aimed to forecast demand for bakery products at “Tiara Rizki” industry in Boyaoge Village Tatanga District of Palu City in 2016. This research was conducted in June 2015.
Gusdian, E. (Eby)
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Metode Double Exponential Smoothing pada Sistem Peramalan Tingkat Kemiskinan Kabupaten Pangkep

open access: yesIlkom Jurnal Ilmiah, 2020
Peramalan adalah kegiatan memperkirakan kejadian yang akan terjadi berdasarkan historical data kuantitatif suatu kejadian. Peramalan sering digunakan oleh pemerintah dalam membuat suatu kebijakan.
Nur Almar' Atussaliha   +2 more
doaj   +1 more source

Beyond the RPA on the cheap: improved correlation energies with the efficient "Radial Exchange Hole" kernel

open access: yes, 2012
The "ACFD-RPA" correlation energy functional has been widely applied to a variety of systems to successfully predict energy differences, and less successfully predict absolute correlation energies.
Gould, Tim
core   +1 more source

Sutte Indicator: an approach to predict the direction of stock market movements [PDF]

open access: yes, 2018
The purpose of this research is to apply technical analysis of Sutte Indicator in stock trading which will assist in the investment decision making process i.e. buying or selling shares. This research takes data of "A" on the Indonesia Stock Exchange(IDX
Ahmar, Ansari Saleh
core   +2 more sources

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