Results 41 to 50 of about 213,848 (240)

A Hybrid Neural Network Model for Short-Term Wind Speed Forecasting

open access: yesEnergies, 2023
This study proposes an effective wind speed forecasting model combining a data processing strategy, neural network predictor, and parameter optimization method.
Shengxiang Lv, Lin Wang, Sirui Wang
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Fuzzy Inference System Mamdani dan the Mean Absolute Percentage Error (MAPE) untuk Prediksi Permintaan Dompet Pulsa pada XL Axiata Depok [PDF]

open access: yesJurnal Informatika Universitas Pamulang, 2017
Kemajuan perkembangan teknologi informasi pada era globalisasi sekarang ini sangat pesat; hal ini menuntut setiap perusahaan untuk dapat saling bersaing dalam dunia bisnis yang dinamis dan penuh persaingan. Pada proses manjaemen permintaan dompet pulsa di XL Axiata cabang Depok memerlukan peramalan yang cukup matang agar dompet pulsa yang diminta ...
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A Unified Family of Percentage-Error Support Vector Regression Models with Symmetric Kernel Extensions

open access: yesMathematics
Support vector regression (SVR) is a well-established kernel-based method for nonlinear regression. However, standard SVR formulations minimize absolute-error losses, which are not consistent with the scale-free, relative-accuracy criteria prevalent in ...
Pablo Benavides-Herrera   +3 more
doaj   +1 more source

A Comparison of Models for Estimating Solar Radiation from Sunshine Duration in Croatia

open access: yesInternational Journal of Photoenergy, 2020
The performance of seventeen sunshine-duration-based models has been assessed using data from seven meteorological stations in Croatia. Conventional statistical indicators are used as numerical indicators of the model performance: mean absolute ...
Tihomir Betti   +3 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Comprehensive deformation study in the new Austrian tunneling technique tunnel utilising artificial neural network model

open access: yesAiBi Revista de Investigación, Administración e Ingeniería
Ground deformation during tunneling projects is one of the complicated concerns that must be constantly monitored to prevent unanticipated damages and human losses.
Shubham Kanojiya, Gopal Krishna Mehta
doaj   +1 more source

Accuracy of sonographic fetal weight estimation in a tertiary care hospital in Bharatpur, Nepal

open access: yesJournal of College of Medical Sciences-Nepal, 2017
Background & Objectives: Among the various methods used in the estimation of intrauterine fetal weight, sonographic fetal weight estimation is the one and has become an important component of antenatal care.
V Natraj Prasad   +2 more
doaj   +1 more source

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