Results 91 to 100 of about 654,693 (352)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

COMP Report: CPQR technical quality control guidelines for use of positron emission tomography/computed tomography in radiation treatment planning

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Positron emission tomography with x‐ray computed tomography (PET/CT) is increasingly being utilized for radiation treatment planning (RTP). Accurate delivery of RT therefore depends on quality PET/CT data. This study covers quality control (QC) procedures required for PET/CT for diagnostic imaging and incremental QC required for RTP.
Ran Klein, Mike Oliver, Dan La Russa, John Agapito, Stewart Gaede, JeanPierre Bissonnette, Arman Rahmim, Carlos Uribe   +7 more
wiley   +1 more source

Analysis of Vaneless Diffuser Stall Instability in a Centrifugal Compressor

International Journal of Turbomachinery, Propulsion and Power, 2017
Numerical simulations based on the large eddy simulation approach were conducted with the aim to explore vaneless diffuser rotating stall instability in a centrifugal compressor.
Elias Sundström, Mihai Mihăescu, Marco Giachi, Elisabetta Belardini, Vittorio Michelassi   +4 more
doaj   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Treatment planning with a 2.5 MV photon beam for radiation therapy

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi, Chris Hayes, Louise Belshaw, Mark Grattan, Rao Khan, James L. Gräfe   +5 more
wiley   +1 more source

No breather theorems for the mean curvature flow [PDF]

arXiv, 2021
In this article we study the breathers of the mean curvature flow in the Euclidean space. A breather is a solution to the mean curvature flow which repeats itself up to isometry and scaling once in a while. We prove several no breather theorems in the noncompact category, that is, under certain conditions, a breather of the mean curvature flow must be ...
arxiv  

Mean curvature flow of Reifenberg sets [PDF]

Geometry & Topology, 2017
In this paper, we prove short time existence and uniqueness of smooth evolution by mean curvature in $\mathbb{R}^{n+1}$ starting from any $n$-dimensional $(\varepsilon,R)$-Reifenberg flat set with $\varepsilon$ sufficiently small. More precisely, we show that the level set flow in such a situation is non-fattening and smooth.
openaire   +4 more sources

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Mean curvature flow solitons from symmetry group viewpoint [PDF]

arXiv, 2022
The symmetry group of the mean curvature flow in general ambient Riemannian manifolds is determined, based on which we define generalized solitons to the mean curvature flow. We also provide examples of homothetic solitons in non-Euclidean surfaces and prove that all the affine solutions to the mean curvature flow are self-similar solutions.
arxiv  

Local existence and uniqueness of skew mean curvature flow [PDF]

, 2019
The Skew Mean Curvature Flow (SMCF) is a Schrödinger-type geometric flow canonically defined on a co-dimension two submanifold, which generalizes the famous vortex filament equation in fluid dynamics.
Chong Song
semanticscholar   +1 more source