Results 111 to 120 of about 43,248 (266)

Approximations of the mean curvature, and the Buet-Rumpf approximate mean curvature flow

CoRR
The aim of this paper is to generalize the work of B. Buet and M. Rumpf on some definition of the approximate mean curvature vector for varifolds, and its associated mean curvature motions for points clouds. We propose a generalization of the definition of the approximate mean curvature vector in two terms: in terms of linear operators and in terms of ...
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

On the structure of singularities of weak mean curvature flows with mean curvature bounds

Journal für die reine und angewandte Mathematik (Crelles Journal)
Abstract This paper studies singularities of mean curvature flows with integral mean curvature bounds H ∈
openaire   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Starshaped hypersurfaces and the mean curvature flow

Manuscripta Mathematica, 1998
The author generalizes a result of \textit{G. Huisken} and \textit{C. Sinestrari} [`Mean curvature flow singularities for mean convex surfaces', Calc. Var. Partial Differ. Equ. 8, No.1, 1-14 (1999)], giving conditions such that under the mean curvature flow a type II singularity develops. Whereas Huisken-Sinestrari's paper gets the result assuming that
openaire   +2 more sources

Performance of various SST models in predicting typical separated flows

Kongqi donglixue xuebao
The phenomenon of flow separation critically influences the flow field structure near aircraft surfaces and their overall performance. This study evaluated the predictive performance of the widely used shear-stress transport (SST) turbulence model and ...
Wenhao Li, Caiyan Rao, Yi Duan, Ding Wang, Yuan Gao, Jian Zhang   +5 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

A comparison principle for singular parabolic equations in the Heisenberg group

Electronic Journal of Differential Equations, 2015
In this work, we prove a comparison principle for singular parabolic equations with boundary conditions in the context of the Heisenberg group. In particular, this result applies to interesting equations, such as the parabolic infinite Laplacian, the
Pablo Ochoa
doaj  

Computational Flow Diverter Implantation—A Comparative Study on Pre-Interventional Simulation and Post-Interventional Device Positioning for a Novel Blood Flow Modulator

Fluids
Due to their effect on aneurysm hemodynamics, flow diverters (FD) have become a routine endovascular therapy for intracranial aneurysms. Since over- and undersizing affect the device’s hemodynamic abilities, selecting the correct device diameter and ...
Maximilian Thormann, Janneck Stahl, Laurel Marsh, Sylvia Saalfeld, Nele Sillis, Andreas Ding, Anastasios Mpotsaris, Philipp Berg, Daniel Behme   +8 more
doaj   +1 more source