Results 111 to 120 of about 265,786 (329)

Improved flow prediction of non-ideal sonic nozzles by CFD-based surrogate modelling

Engineering Applications of Computational Fluid Mechanics
The use of sonic nozzles as a high-precision standard for gas flow measurements in various engineering and metrological applications is well-established.
Sebastian Weiss, Bodo Mickan, Kilian Oberleithner, Markus Bär, Sonja Schmelter   +4 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

On the singular set of mean curvature flows with Neumann free boundary conditions [PDF]

, 2010
Amos N. Koeller
openalex   +1 more source

Ruled surfaces as translating solitons of the inverse mean curvature flow in the three-dimensional Lorentz-Minkowski space [PDF]

, 2023
Gregório Silva Neto, Vanessa Vieira da Silva   +1 more
openalex   +1 more source

Translating annuli for mean curvature flow

Advances in Mathematics
We construct a family of complete, properly embedded, annular translators $M$ such that $M$ lies in a slab and is invariant under reflections in the vertical coordinate planes. Each translator in the family is asymptotic as $z\to -\infty$ to four vertical planes $\{y= \pm b\}$ and $\{y= \pm B\}$, where $00$, there is a translator in the family with ...
Hoffman, David, Martín, Francisco, White, Brian   +2 more
openaire   +3 more sources

Examples of Ricci-Mean Curvature Flows [PDF]

The Journal of Geometric Analysis, 2017
18 pages, 1 figure, 1 ...
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Some remarks on Huisken's monotonicity formula for mean curvature flow [PDF]

, 2017
Carlo Mantegazza, Annibale Magni
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

CFD-based investigation of turbulent flow behavior in 90-deg pipe bends

Journal of Applied Research in Technology & Engineering
This work investigated the influence of bend curvature on the parameters of turbulent flow through a 90° pipe bend using the numerical CFD method, implemented in ANSYS Fluent. The numerical predictions were validated to be in good agreement with existing
Rilwan Kayode Apalowo, Cletus John Akisin   +1 more
doaj   +1 more source