Results 131 to 140 of about 255,201 (317)
FEBS Open Bio, EarlyView.Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash +6 more
wiley +1 more source
Nitric oxide‐forming nitrite reductases in the anaerobic ammonium oxidizer Kuenenia stuttgartiensis
FEBS Open Bio, EarlyView.Anammox bacteria remove fixed nitrogen from their environment via anaerobic ammonium oxidation (anammox) with nitrite as electron acceptor and dinitrogen gas as product. The first anammox step is the conversion of nitrite to nitric oxide by nitrite reductase.
Femke J. Vermeir +4 more
wiley +1 more source
Interface evolution of microdroplets in flow-focusing channels with varying aspect ratios
FlowThis study combines experimental observations and numerical simulations to comprehensively analyse the interface evolution of confined droplets in microfluidic devices with flow-focusing junctions under different aspect ratios.
Luyao He +3 more
doaj +1 more source
The Inverse Mean Curvature Flow and the Riemannian Penrose Inequality [PDF]
, 2001 Gerhard Huisken, Tom Ilmanen
openalex +1 more source
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
FEBS Open Bio, EarlyView.The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu +12 more
wiley +1 more source
Planar Waves of the Buffered Bistable System
Abstract and Applied Analysis, 2013 This paper is concerned with the large time behavior of disturbed planar fronts in the buffered bistable system in ℝn (n≥2). We first show that the large time behavior of the disturbed fronts can be approximated by that of the mean curvature flow with a
Xiaohuan Wang, Guangying Lv
doaj +1 more source
FEBS Open Bio, EarlyView.Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
Impact of poloidal convective cells on momentum flux in tokamaks
New Journal of Physics, 2017 Radial fluxes of parallel momentum due to $E\times B$ and magnetic drifts are shown to be correlated in tokamak plasmas. This correlation comes from the onset of poloidal convective cells generated by turbulence.
X Garbet +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source