Results 131 to 140 of about 265,786 (329)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Planar Waves of the Buffered Bistable System

open access: yesAbstract and Applied Analysis, 2013
This paper is concerned with the large time behavior of disturbed planar fronts in the buffered bistable system in ℝn (n≥2). We first show that the large time behavior of the disturbed fronts can be approximated by that of the mean curvature flow with a
Xiaohuan Wang, Guangying Lv
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Annuloids and Δ-wings

open access: yesAdvanced Nonlinear Studies
We describe new annular examples of complete translating solitons for the mean curvature flow and how they are related to a family of translating graphs, the Δ-wings.
Hoffman David   +2 more
doaj   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Mean Curvature Flow with Triple Junctions in Higher Space Dimensions [PDF]

open access: green, 2013
Daniel Depner   +2 more
openalex   +1 more source

Mean curvature flow from conical singularities

open access: yesInventiones mathematicae
AbstractWe prove Ilmanen’s resolution of point singularities conjecture by establishing short-time smoothness of the level set flow of a smooth hypersurface with isolated conical singularities. This shows how the mean curvature flow evolves through asymptotically conical singularities.
Chodosh, Otis   +2 more
openaire   +2 more sources

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