Results 81 to 90 of about 265,786 (329)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Mean curvature flow on Ricci solitons [PDF]
Journal of Physics A: Mathematical and Theoretical, 2009 19 ...
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Stochastic mean curvature flow
, 2020 In this thesis we study a stochastically perturbed mean curvature flow (SMCF). In case of graphs, existence of weak solutions has already been established for one-dimensional and two-dimensional periodic surfaces with a spatially homogeneous perturbation. We extend this result by proving existence of solutions in arbitrary dimensions perturbed by noise
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Advances in Nonlinear AnalysisOur purpose is to establish nonexistence results concerning complete noncompact mean curvature flow solitons with polynomial volume growth immersed in certain semi-Riemannian warped products, under mild constraints on the warping and soliton functions ...
Batista Márcio +3 more
doaj +1 more source
Swampland, gradient flow and infinite distance
Journal of High Energy Physics, 2020 In the first part of this paper we will work out a close and so far not yet noticed correspondence between the swampland approach in quantum gravity and geometric flow equations in general relativity, most notably the Ricci flow.
Alex Kehagias +2 more
doaj +1 more source
Mean curvature flow without singularities
, 2012 We study graphical mean curvature flow of complete solutions defined on subsets of Euclidean space. We obtain smooth long time existence. The projections of the evolving graphs also solve mean curvature flow.
Schnürer, Oliver C. +1 more
core
Singular perturbations of mean curvature flow
Journal of Differential Geometry, 2007 We introduce a regularization method for mean curvature flow of a submanifold of arbitrary codimension in the Euclidean space, through higher order equations. We prove that the regularized problems converge to the mean curvature flow for all times before the first singularity.
GIOVANNI BELLETTINI +2 more
openaire +9 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source