Results 101 to 110 of about 211,213 (315)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Advances in Nonlinear Analysis, 2023 This work is concerned with the nonexistence of nontrivial nonnegative weak solutions for a quasilinear parabolic differential inequality with weighted nonlocal source term in the whole space, which involves weighted polytropic filtration operator or ...
Li Yuepeng, Fang Zhong Bo
doaj +1 more source
Boundary value problems for noncompact boundaries of Spinᶜ manifolds and spectral estimates
, 2014 We study boundary value problems for the Dirac operator on Riemannian Spin$^c$ manifolds of bounded geometry and with noncompact boundary. This generalizes a part of the theory of boundary value problems by C. B\"ar and W. Ballmann for complete manifolds
Grosse, N., Nakad, R.
core +2 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Phasefield theory for fractional diffusion-reaction equations and applications [PDF]
, 2009 This paper is concerned with diffusion-reaction equations where the classical diffusion term, such as the Laplacian operator, is replaced with a singular integral term, such as the fractional Laplacian operator.
Cyril Imbert +2 more
core +2 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Dirichlet Problem with Mean Curvature Operator in Minkowski Space – a Variational Approach
Advanced Nonlinear Studies, 2014 Abstract In this paper we consider the Dirichlet problem with mean curvature operator in Minkowski space : where Ω ⊂ ℝN is a smooth open bounded set and f : Ω × ℝ → ℝ is a Carathéodory function.
Bereanu, C., Jebelean, P., Mawhin, J.
openaire +1 more source