Results 101 to 110 of about 428,360 (302)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Improved asymptotics of a decreasing mean residual life estimator

open access: yes, 2014
Click on the DOI link to access the article (may not be free).The mean residual life of a life distribution, X, with a finite mean is defined by M(t) = E[X - t|X > t] for t > 0. Kochar etal.
Lorenzo, Edgardo, Mukerjee, Hari
core   +1 more source

Properties of Residual Cumulative Sharma–Taneja–Mittal Model and Its Extensions in Reliability Theory with Applications to Human Health Analysis and Mixed Coherent Mechanisms

open access: yesEntropy
The entropy measure of residual cumulative Sharma–Taneja–Mittal is an alternative measure of uncertainty for residual cumulative entropy. This study investigates further theoretical properties and develops nonparametric estimation procedures for the ...
Mohamed Said Mohamed, Hanan H. Sakr
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

HIV/Aids Relative Survival and Mean Residual Life Analysis

open access: yes, 2007
HIV/Aids Relative Survival and Mean Residual Life Analysis BY XINJIAN ZHANG Under the Direction of Gengsheng (Jeff) Qin and Ruiguang (Rick) Song ABSTRACT Generalized linear models with Poisson ...
Zhang, Xinjian
core   +1 more source

Pemodelan Mean Residual Life Dengan Adanya Resiko Persaingan

open access: yes, 2012
The addition of a constant competing risk corresponding to an additional, usually less significant, source of failure, frequently improves the fit in reliability and sur- vival analysis.
Amalia
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Statistical inference on residual life

open access: yes, 2014
This is a monograph on the concept of residual life, which is an alternative summary measure of time-to-event data, or survival data. The mean residual life has been used for many years under the name of life expectancy, so it is a natural concept for ...
Jeong, Jong-Hyeon
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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