Results 41 to 50 of about 613,752 (314)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Linearization of randomly excited nonlinear systems by using local mean square error criterion
Vietnam Journal of Mechanics, 2000 The paper presents the analysis of three non-linear systems under random excitation by using Local Mean Square Error Criterion which is an extension of Gaussian Equivalent Linearization proposed by Caughey.
Luu Xuan Hung
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Alternating minimum mean square error hybrid beamforming algorithm in mmWave MIMO system
Dianxin kexue, 2017 The two-stage hybrid beamforming architecture can solve the problem of limited number of RF chains effectively.However,it is still difficult to design a hybrid beamforming algorithm with better performance.In order to achieve higher spectral efficiency ...
Min SHEN, Hao XU, Yun HE, Pengguang ZHOU
doaj +2 more sources
Mean squared error of empirical predictor
The Annals of Statistics, 2004 The term ``empirical predictor'' refers to a two-stage predictor of a linear combination of fixed and random effects. In the first stage, a predictor is obtained but it involves unknown parameters; thus, in the second stage, the unknown parameters are replaced by their estimators.
Das, Kalyan +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
On mean square of the error term of a multivariable divisor function
AIMS MathematicsLet $ \tau(n) $ be the Dirichlet divisor function and $ k\geqslant2 $ be a fixed integer. We give an asymptotic formula of the mean square of$ \begin{equation*} \Delta_k(x) = \sum\limits_{n_1, \cdots, n_k\leqslant x}\tau(n_1 \cdots n_k)-x^kP_k(\log x ...
Zhen Guo
doaj +1 more source
LPI Optimization Framework for Radar Network Based on Minimum Mean-Square Error Estimation
Entropy, 2017 This paper presents a novel low probability of intercept (LPI) optimization framework in radar network by minimizing the Schleher intercept factor based on minimum mean-square error (MMSE) estimation.
Ji She +3 more
doaj +1 more source
IEEE Access, 2020 This work proposes novel techniques toward the design of optimal pilot sequences to perform channel estimation in block transmission systems over wideband frequency selective wireless fading channels.
Manjeer Majumder, Aditya K. Jagannatham
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source